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T van der Poll

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Articles 227
Citations 5529
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Recent Articles
1.
Slim M, Turgman O, van Vught L, van der Poll T, Wiersinga W
Eur J Intern Med . 2023 Nov; 121:9-16. PMID: 37919123
Sepsis remains a critical global health issue, demanding novel therapeutic strategies. Traditional immunomodulation treatments such as corticosteroids, specific modifiers of cytokines, complement or coagulation, growth factors or immunoglobulins, have so...
2.
Leemans J, Stokman G, Claessen N, Rouschop K, Teske G, Kirschning C, et al.
J Am Soc Nephrol . 2023 Mar; 16(12):3452-3454. PMID: 37000940
No abstract available.
3.
Ramirez-Moral I, Yu X, Butler J, van Weeghel M, Otto N, Ferreira B, et al.
Mucosal Immunol . 2021 Feb; 14(3):594-604. PMID: 33542495
Human bronchial epithelial (HBE) cells play an essential role during bacterial infections of the airways by sensing pathogens and orchestrating protective immune responses. We here sought to determine which metabolic...
4.
Wiersinga W, van Zanten A, Kaasjager K, van der Poll T
Ned Tijdschr Geneeskd . 2017 Sep; 161:D1551. PMID: 28914210
- Incidence of sepsis is increasing, partly due to an ageing population, increased use of immunosuppressants, and antibiotic resistance. Sepsis survival has improved substantially, in part because of continuously improving...
5.
Bos L, Schouten L, van Vught L, Wiewel M, Ong D, Cremer O, et al.
Thorax . 2017 Apr; 72(10):876-883. PMID: 28450529
Rationale: We hypothesised that patients with acute respiratory distress syndrome (ARDS) can be clustered based on concentrations of plasma biomarkers and that the thereby identified biological phenotypes are associated with...
6.
Janssen S, Osbak K, Holman R, Hermans S, Moekotte A, Knap M, et al.
Infection . 2017 Mar; 45(5):669-676. PMID: 28349491
There is a paucity of data on the immune reconstitution inflammatory syndrome (IRIS) in the Central African region. We followed ART-naive HIV-infected patients initiating antiretroviral therapy in an HIV clinic...
7.
Claushuis T, de Stoppelaar S, Stroo I, Roelofs J, Ottenhoff R, van der Poll T, et al.
J Thromb Haemost . 2017 Jan; 15(4):744-757. PMID: 28092405
Summary: Background Innate immunity and coagulation are closely linked during sepsis. Their interaction can be detrimental to the outcome because of microvascular failure but can also enhance host defense. The...
8.
Prins J, van der Poll T
Ned Tijdschr Geneeskd . 2016 Oct; 160:D957. PMID: 27734780
Better use of current antibiotics is warranted to curb increasing antimicrobial resistance rates. Procalcitonin guidance can safely reduce antibiotic usage when used to initiate or discontinue antibiotics in adult patients...
9.
Anas A, Yang J, de Boer J, Roelofs J, Hou B, de Vos A, et al.
Clin Exp Immunol . 2016 Sep; 187(2):204-212. PMID: 27625307
Asthma is a highly prevalent chronic allergic inflammatory disease of the airways affecting people worldwide. House dust mite (HDM) is the most common allergen implicated in human allergic asthma. HDM-induced...
10.
Majoor C, Sneeboer M, de Kievit A, Meijers J, van der Poll T, Lutter R, et al.
J Thromb Haemost . 2016 Jan; 14(4):716-23. PMID: 26791678
Background: Corticosteroids have been associated with an increased risk of venous thromboembolism in patients treated for inflammatory diseases. It is unclear whether the thrombotic risk is induced by the inflammation...