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P Decuzzi

Explore the profile of P Decuzzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 890
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Recent Articles
1.
Pesce C, Goldoni L, Papa V, Palange A, Di Mascolo D, Caliceti P, et al.
Mol Pharm . 2024 May; 21(6):2937-2948. PMID: 38750625
Polymers are extensively used for the realization of drug delivery systems across multiple scales, from nanomedicines to microparticles and macroscopic implantable devices, for their favorable biodegradation profiles and tunable physicochemical...
2.
Coclite A, Mollica H, Ranaldo S, Pascazio G, de Tullio M, Decuzzi P
Microfluid Nanofluidics . 2020 Feb; 21(11):168. PMID: 32009866
A fundamental step in the rational design of vascular targeted particles is the firm adhesion at the blood vessel walls. Here, a combined lattice Boltzmann-immersed boundary model is presented for...
3.
Nabil M, Decuzzi P, Zunino P
R Soc Open Sci . 2015 Nov; 2(10):150447. PMID: 26587251
We derive a sophisticated mathematical model for coupled heat and mass transport in the tumour microenvironment and we apply it to study nanoparticle delivery and hyperthermic treatment of cancer. The...
4.
Sciume G, Santagiuliana R, Ferrari M, Decuzzi P, Schrefler B
Phys Biol . 2014 Nov; 11(6):065004. PMID: 25427284
Existing tumor growth models based on fluid analogy for the cells do not generally include the extracellular matrix (ECM), or if present, take it as rigid. The three-fluid model originally...
5.
Key J, Kim Y, Tatulli F, Palange A, ONeill B, Aryal S, et al.
Clin Transl Imaging . 2014 Nov; 2(5):427-437. PMID: 25379506
Malignancies of the lungs, both primary and metastatic, are the leading cause of death worldwide. Over 1.5 million new cases of primary lung cancer are diagnosed annually worldwide with a...
6.
Sciume G, Shelton S, Gray W, Miller C, Hussain F, Ferrari M, et al.
New J Phys . 2014 Feb; 15:015005. PMID: 24554920
Several mathematical formulations have analyzed the time-dependent behaviour of a tumor mass. However, most of these propose simplifications that compromise the physical soundness of the model. Here, multiphase porous media...
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Sciume G, Shelton S, Gray W, Millers C, Hussain F, Ferrari M, et al.
Mol Cell Biomech . 2013 Jan; 9(3):193-212. PMID: 23285734
Multiphase porous media mechanics is used for modeling tumor growth, using governing equations obtained via the thermodynamically constrained averaging theory (TCAT). This approach incorporates the interaction of more phases than...
9.
Decuzzi P, Godin B, Tanaka T, Lee S, Chiappini C, Liu X, et al.
J Control Release . 2009 Oct; 141(3):320-7. PMID: 19874859
Understanding how size and shape can affect the biodistribution of intravascularly injected particles is of fundamental importance both for the rational design of delivery systems and from a standardization and...
10.
Gentile F, Chiappini C, Fine D, Bhavane R, Peluccio M, Cheng M, et al.
J Biomech . 2008 Jun; 41(10):2312-8. PMID: 18571181
The margination dynamics of microparticles with different shapes has been analyzed within a laminar flow mimicking the hydrodynamic conditions in the microcirculation. Silica spherical particles, quasi-hemispherical and discoidal silicon particles...