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P Dande

Explore the profile of P Dande including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 37
Followers 0
Related Specialties
Biochemistry
Oncology
Hematology
Top 10 Co-Authors
B Gold
G Fronza
A M Soto
D Shah
F X Chen
G Liang
A Abbondandolo
L Levati
H Hashimoto
B I Kankia
Published In
Biochemistry
Nucleic Acids Res
J Biol Chem
Leukemia
Affiliations
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Recent Articles
1.
Incorporation of a cationic aminopropyl chain in DNA hairpins: thermodynamics and hydration
Soto A, Kankia B, Dande P, Gold B, Marky L
Nucleic Acids Res . 2001 Aug; 29(17):3638-45. PMID: 11522834
We report on the physicochemical effects resulting from incorporating a 5-(3-aminopropyl) side chain onto a 2'-deoxyuridine (dU) residue in a short DNA hairpin. A combination of spectroscopy, calorimetry, density and...
2.
Evidence in Escherichia coli that N3-methyladenine lesions induced by a minor groove binding methyl sulfonate ester can be processed by both base and nucleotide excision repair
Shah D, Kelly J, Zhang Y, Dande P, Martinez J, Ortiz G, et al.
Biochemistry . 2001 May; 40(6):1796-803. PMID: 11327842
It has been previously reported that a neutral DNA equilibrium binding agent based on an N-methylpyrrolecarboxamide dipeptide (lex) and modified with an O-methyl sulfonate ester functionality (MeOSO(2)-lex) selectively affords N3-methyladenine...
3.
Cytotoxic and clastogenic effects of a DNA minor groove binding methyl sulfonate ester in mismatch repair deficient leukemic cells
Tentori L, Vernole P, Lacal P, Madaio R, Portarena I, Levati L, et al.
Leukemia . 2000 Aug; 14(8):1451-9. PMID: 10942242
Mismatch repair deficiency contributes to tumor cell resistance to O6-guanine methylating compounds and to other antineoplastic agents. Here we demonstrate that MeOSO2(CH2)2-lexitropsin (Me-Lex), a DNA minor groove alkylating compound which...
4.
Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent
Kelly J, Inga A, Chen F, Dande P, Shah D, Monti P, et al.
J Biol Chem . 1999 Jun; 274(26):18327-34. PMID: 10373436
Me-lex, a methyl sulfonate ester appended to a neutral N-methylpyrrolecarboxamide-based dipeptide, was synthesized to preferentially generate N3-methyladenine (3-MeA) adducts which are expected to be cytotoxic rather than mutagenic DNA lesions....
5.
Regioselective effect of zwitterionic DNA substitutions on DNA alkylation: evidence for a strong side chain orientational preference
Dande P, Liang G, Chen F, Roberts C, NELSON M, Hashimoto H, et al.
Biochemistry . 1997 May; 36(20):6024-32. PMID: 9166773
The incorporation of zwitterionic residues (5-substituted omega-aminoalkyl-2'-deoxypyrimidines) into DNA has been reported to bend DNA as measured by aberrant gel mobility [Strauss et al. (1996) Proc. Natl. Acad. Sci. U.S.A....