P D Robbins
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Explore the profile of P D Robbins including associated specialties, affiliations and a list of published articles.
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275
Citations
5656
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Recent Articles
11.
Gaddy D, Riedel M, Bertera S, Kieffer T, Robbins P
Gene Ther
. 2011 Nov;
19(8):791-9.
PMID: 22089495
Type-I diabetes is a chronic disease mediated by autoimmune destruction of insulin-producing β-cells. Although progress has been made towards improving diabetes-associated pathologies and the quality of life for those living...
12.
Evans C, Ghivizzani S, Robbins P
J Cell Physiol
. 2011 Sep;
227(2):416-20.
PMID: 21948071
Orthopedic gene therapy has been the topic of considerable research for two decades. The preclinical data are impressive and many orthopedic conditions are well suited to genetic therapies. But there...
13.
Pola E, Nasto L, Tampieri A, Lattanzi W, Di Giacomo G, Colangelo D, et al.
Int J Immunopathol Pharmacol
. 2011 Jun;
24(1 Suppl 2):139-42.
PMID: 21669153
The debate is still ongoing about the long term effects of the mininvasive vertebral augmentation techniques and their usefulness in treating more complex cases where a bone inducing effect more...
14.
Tang Y, Reay D, Salay M, Mi M, Clemens P, Guttridge D, et al.
Gene Ther
. 2010 Aug;
17(12):1476-83.
PMID: 20720575
The IκB kinase (IKKα, β and the regulatory subunit IKKγ) complex regulates nuclear factor of κB (NF-κB) transcriptional activity, which is upregulated in many chronic inflammatory diseases. NF-κB signaling promotes...
15.
Riedel M, Gaddy D, Asadi A, Robbins P, Kieffer T
Gene Ther
. 2009 Oct;
17(2):171-80.
PMID: 19865180
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that performs a wide array of well-characterized antidiabetic actions, including stimulation of glucose-dependent insulin secretion, upregulation of insulin gene expression and improvements in...
16.
Evans C, Ghivizzani S, Robbins P
Gene Ther
. 2009 Aug;
16(8):944-52.
PMID: 19675584
Gene therapies directed toward the treatment of arthritis and tissue repair continue to be the most active areas of research for bone and joint diseases. In the past 2 years,...
17.
Reay J, Kim S, Lockhart E, Kolls J, Robbins P
Cancer Gene Ther
. 2009 Apr;
16(10):776-85.
PMID: 19390568
Interleukin 23 (IL-23) is a member of the IL-12 family of heterodimeric cytokines, composed of p19 and p40 subunits, which exhibits immunostimulatory properties similar to IL-12. IL-23 has been shown...
18.
Thomson A, Robbins P
Ann Rheum Dis
. 2008 Dec;
67 Suppl 3:iii90-6.
PMID: 19022823
Dendritic leucocytes are professional antigen-presenting cells with inherent tolerogenic properties and are regarded as critical regulators of innate and adaptive immunity. Modification of dendritic cells (DCs) in the laboratory can...
19.
Lattanzi W, Parrilla C, Fetoni A, Logroscino G, Straface G, Pecorini G, et al.
Gene Ther
. 2008 Jul;
15(19):1330-43.
PMID: 18633445
Local gene transfer of the human Lim mineralization protein (LMP), a novel intracellular positive regulator of the osteoblast differentiation program, can induce efficient bone formation in rodents. To develop a...
20.
Grove C, Robbins P, Kermode A
J Clin Neurosci
. 2008 Jul;
15(9):1056-8.
PMID: 18614371
We present a patient with subacute progressive paraparesis secondary to intravascular lymphoma restricted to the spinal cord where initial laboratory and imaging studies were inconclusive. We emphasise the importance of...