P D Darbre
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Explore the profile of P D Darbre including associated specialties, affiliations and a list of published articles.
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74
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789
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Recent Articles
1.
Barr L, Alamer M, Darbre P
J Appl Toxicol
. 2018 Apr;
38(8):1112-1120.
PMID: 29658634
The human population is widely exposed to benzophenone-3 (BP-3), octylmethoxycinnamate (OMC), 4-methylbenzilidenecamphor (4-MBC) and homosalate from their use in consumer goods to absorb ultraviolet (UV) light. Their oestrogenic activity and...
2.
Darbre P
Morphologie
. 2016 Mar;
100(329):65-74.
PMID: 26997127
The human population is exposed to aluminium (Al) from diet, antacids and vaccine adjuvants, but frequent application of Al-based salts to the underarm as antiperspirant adds a high additional exposure...
3.
Farasani A, Darbre P
J Inorg Biochem
. 2015 Aug;
152:186-9.
PMID: 26319584
Use of underarm aluminium (Al)-based antiperspirant salts may be a contributory factor in breast cancer development. At the 10th Keele meeting, Al was reported to cause anchorage-independent growth and double...
4.
Barr L, Metaxas G, Harbach C, Savoy L, Darbre P
J Appl Toxicol
. 2012 Jan;
32(3):219-32.
PMID: 22237600
The concentrations of five esters of p-hydroxybenzoic acid (parabens) were measured using HPLC-MS/MS at four serial locations across the human breast from axilla to sternum using human breast tissue collected...
5.
Darbre P, Pugazhendhi D, Mannello F
J Inorg Biochem
. 2011 Nov;
105(11):1484-8.
PMID: 22099158
The human breast is exposed to aluminium from many sources including diet and personal care products, but dermal application of aluminium-based antiperspirant salts provides a local long-term source of exposure....
6.
Charles A, Darbre P
J Appl Toxicol
. 2009 Apr;
29(5):422-34.
PMID: 19338011
Benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) are added to bodycare cosmetics used around the human breast. We report here that all three compounds possess oestrogenic activity in assays using...
7.
Sadler A, Pugazhendhi D, Darbre P
J Steroid Biochem Mol Biol
. 2009 Jan;
114(1-2):21-32.
PMID: 19167489
Over the years, the MCF7 human breast cancer cell line has provided a model system for the study of cellular and molecular mechanisms in oestrogen regulation of cell proliferation and...
8.
Pugazhendhi D, Watson K, Mills S, Botting N, Pope G, Darbre P
J Endocrinol
. 2008 May;
197(3):503-15.
PMID: 18492816
The phytoestrogens genistein, daidzein and the daidzein metabolite equol have been shown previously to possess oestrogen agonist activity. However, following consumption of soya diets, they are found in the body...
9.
Gee R, Charles A, Taylor N, Darbre P
J Appl Toxicol
. 2007 Nov;
28(1):78-91.
PMID: 17992702
As a consequence of its widespread use as an antimicrobial agent in consumer goods, triclosan has become distributed ubiquitously across the ecosystem, and recent reports that it can cause endocrine...
10.
Pugazhendhi D, Sadler A, Darbre P
J Appl Toxicol
. 2006 Nov;
27(1):67-77.
PMID: 17121429
Since the alkyl esters of p-hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested that they could contribute to an...