P C Singhal
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Explore the profile of P C Singhal including associated specialties, affiliations and a list of published articles.
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184
Citations
925
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Recent Articles
1.
Vashistha H, Marrero L, Reiss K, Cohen A, Malhotra A, Javed T, et al.
Am J Physiol Renal Physiol
. 2018 Sep;
315(6):F1833-F1842.
PMID: 30207172
The p66ShcA protein controls cellular responses to oxidative stress, senescence, and apoptosis. Here, we test the hypothesis that aging phenotype(s) commonly associated with the broad category of chronic kidney disease...
2.
Mikulak J, Teichberg S, Arora S, Kumar D, Yadav A, Salhan D, et al.
Am J Physiol Renal Physiol
. 2010 Jul;
299(3):F664-73.
PMID: 20630938
Human immunodeficiency virus (HIV)-1 has been demonstrated to contribute to the pathogenesis of HIV-associated nephropathy. In renal biopsy studies, podocytes have been reported to be infected by HIV-1. However, the...
3.
Ranjan R, Shah H, Siu J, Varghese E, Bhaskaran M, Reddy K, et al.
Clin Nephrol
. 2003 Jan;
58(6):423-30.
PMID: 12508964
Background: The mononuclear phagocyte system plays an important role in host defense. Since dialysis patients have been reported to show enhanced leukocytes apoptosis, we evaluated the mechanism of increased apoptosis...
4.
Bhaskaran M, Ranjan R, Shah H, Siu J, Colvin R, Radhakrishnan N, et al.
Clin Nephrol
. 2002 Apr;
57(3):221-9.
PMID: 11924754
Lymphopenia is a common finding in dialysis patients. Since infection rate and mortality associated with infection are high in dialysis patients, lymphopenia may be one of the contributing factors. In...
5.
Bhaskaran M, Reddy K, Sharma S, Singh J, Radhakrishnan N, Kapasi A, et al.
J Infect Dis
. 2001 Dec;
184(12):1524-31.
PMID: 11740727
The effect of morphine on the degradation of the host defense barrier in rats and mice was studied. Mice received either 3 or 11 doses of morphine. Mice receiving 11...
6.
Nahar N, Shah H, Siu J, Colvin R, Bhaskaran M, Ranjan R, et al.
Clin Nephrol
. 2001 Aug;
56(1):52-9.
PMID: 11499659
Patients on hemodialysis are prone to infection. Neutrophils are the host's first line of defense against certain invading pathogenic microorganisms. Since apoptotic neutrophils are functionally compromised we examined the effect...
7.
Kapoor R, Reddy K, Liatsikos E, Smith A, Singhal P
J Endourol
. 2001 Apr;
15(2):155-9.
PMID: 11325085
Background And Purpose: Urinary tract infection has been associated with renal interstitial scarring and ureteral wall fibrosis. The mechanism of progression of scarring despite attenuation of the primary insult is...
8.
Nwakoby I, Reddy K, Patel P, Shah N, Sharma S, Bhaskaran M, et al.
Infect Immun
. 2001 Apr;
69(5):3343-9.
PMID: 11292757
In the presence of infection, neutropenia is considered to be a marker of poor prognosis; conversely, neutrophilia may not be a determinant of a better prognosis. Since apoptotic neutrophils are...
9.
Kapasi A, Fan S, Singhal P
Am J Physiol Renal Physiol
. 2001 Feb;
280(2):F333-42.
PMID: 11208609
Focal glomerulosclerosis (FGS) is the predominant glomerular lesion in patients with human immunodeficiency virus (HIV)-associated nephropathy. Initial mesangial cell hyperplasia and subsequent hypoplasia are common features of FGS. In the...
10.
Sanwal V, Pandya M, Bhaskaran M, Franki N, Reddy K, Ding G, et al.
Exp Mol Pathol
. 2001 Feb;
70(1):54-64.
PMID: 11170791
Glomerular epithelial cell (GEC) injury has been considered to play an important role in puromycin aminonucleoside (PAN)-induced nephrosis. We studied the effect of PAN on rat as well as human...