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P C Guest

Explore the profile of P C Guest including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 786
Followers 0
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Recent Articles
1.
Steiner J, Bernstein H, Guest P, Summergrad P, Oxenkrug G
Eur Neuropsychopharmacol . 2020 Aug; 41:167-168. PMID: 32855025
No abstract available.
2.
Wesseling H, Xu B, Want E, Holmes E, Guest P, Karayiorgou M, et al.
Mol Psychiatry . 2016 Mar; 22(3):384-395. PMID: 27001617
Deletions on chromosome 22q11.2 are a strong genetic risk factor for development of schizophrenia and cognitive dysfunction. We employed shotgun liquid chromatography-mass spectrometry (LC-MS) proteomic and metabonomic profiling approaches on...
3.
Chan M, Krebs M, Cox D, Guest P, Yolken R, Rahmoune H, et al.
Transl Psychiatry . 2015 Jul; 5:e601. PMID: 26171982
Recent research efforts have progressively shifted towards preventative psychiatry and prognostic identification of individuals before disease onset. We describe the development of a serum biomarker test for the identification of...
4.
van Beveren N, Schwarz E, Noll R, Guest P, Meijer C, de Haan L, et al.
Transl Psychiatry . 2014 Aug; 4:e430. PMID: 25158005
Molecular abnormalities in metabolic, hormonal and immune pathways are present in peripheral body fluids of a significant subgroup of schizophrenia patients. The authors have tested whether such disturbances also occur...
5.
Ernst A, Sharma A, Elased K, Guest P, Rahmoune H, Bahn S
Transl Psychiatry . 2013 May; 3:e263. PMID: 23715298
The db/db mouse is a widely used preclinical model in diabetes research. Recent studies have shown that these mice also display aspects of psychosis and depression-like behaviors as seen in...
6.
Martins-de-Souza D, Guest P, Harris L, Vanattou-Saifoudine N, Webster M, Rahmoune H, et al.
Transl Psychiatry . 2012 Jul; 2:e87. PMID: 22832852
Major depressive disorder (MDD) is a leading cause of disability worldwide and results tragically in the loss of almost one million lives in Western societies every year. This is due...
7.
Schwarz E, Guest P, Steiner J, Bogerts B, Bahn S
Transl Psychiatry . 2012 Jul; 2:e82. PMID: 22832819
The current inability of psychiatric medicine to objectively select the most appropriate treatment or to predict imminent relapse are major factors contributing to the severity and clinical burden of schizophrenia....
8.
Schwarz E, Guest P, Rahmoune H, Harris L, Wang L, Leweke F, et al.
Mol Psychiatry . 2011 Apr; 17(5):494-502. PMID: 21483431
Biomarkers are now used in many areas of medicine but are still lacking for psychiatric conditions such as schizophrenia (SCZ). We have used a multiplex molecular profiling approach to measure...
9.
Chan M, Tsang T, Harris L, Guest P, Holmes E, Bahn S
Mol Psychiatry . 2010 Oct; 16(12):1189-202. PMID: 20921955
Extensive research has been conducted on post-mortem brain tissue in schizophrenia (SCZ), particularly the dorsolateral prefrontal cortex (DLPFC). However, to what extent the reported changes are due to the disorder...
10.
Schwarz E, Guest P, Rahmoune H, Wang L, Levin Y, Ingudomnukul E, et al.
Mol Psychiatry . 2010 Sep; 16(12):1213-20. PMID: 20877284
Autism spectrum conditions have been hypothesized to be an exaggeration of normal male low-empathizing and high-systemizing behaviors. We tested this hypothesis at the molecular level by performing comprehensive multi-analyte profiling...