P B Dirks
Overview
Explore the profile of P B Dirks including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
710
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mack S, Witt H, Piro R, Gu L, Zuyderduyn S, Stutz A, et al.
Nature
. 2014 Feb;
506(7489):445-50.
PMID: 24553142
Ependymomas are common childhood brain tumours that occur throughout the nervous system, but are most common in the paediatric hindbrain. Current standard therapy comprises surgery and radiation, but not cytotoxic...
2.
Clarke I, Dirks P
Oncogene
. 2003 Feb;
22(5):722-33.
PMID: 12569364
Aberrant receptor tyrosine kinase signaling plays an important role in the molecular pathogenesis of brain tumors. We have been studying a previously identified human glioblastoma-derived PDGFR-alpha mutant that has an...
3.
Glioma migration: clues from the biology of neural progenitor cells and embryonic CNS cell migration
Dirks P
J Neurooncol
. 2001 Nov;
53(2):203-12.
PMID: 11716071
Neural stem cells have recently come to the forefront in neurobiology because of the possibilities for CNS repair by transplantation. Further understanding of the biology of these cells is critical...
4.
Ivanchuk S, Mondal S, Dirks P, Rutka J
J Neurooncol
. 2001 Jun;
51(3):219-29.
PMID: 11407594
The unique INK4A/ARF locus at chromosome 9p21 encodes two distinct proteins that intimately link the pRB and p53 tumour suppressor pathways. p16INK4A has been identified as an inhibitor of the...
5.
Mainprize T, Taylor M, Rutka J, Dirks P
J Neurooncol
. 2001 Jun;
51(3):205-18.
PMID: 11407593
The cell cycle is a precisely controlled cellular program that ensures normal cellular proliferation and development. The cyclin-dependant kinases (CDK) are molecules central to the continued progression through the cell-cycle...
6.
Murakami M, Dirks P, Hubbard S, Rutka J
Int J Oncol
. 2001 Apr;
18(5):1027-33.
PMID: 11295052
We have investigated the adhesion of the human fibrosarcoma cell line, HT-1080, transfected with glial fibrillary acidic protein (GFAP) to a variety of extracellular matrix macromolecules (ECM) including collagen type...
7.
Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence
Tsugu A, Sakai K, Dirks P, Jung S, Weksberg R, Fei Y, et al.
Am J Pathol
. 2000 Sep;
157(3):919-32.
PMID: 10980131
Astrocytic tumors frequently exhibit defects in the expression or activity of proteins that control cell-cycle progression. Inhibition of kinase activity associated with cyclin/cyclin-dependent kinase co-complexes by cyclin-dependent kinase inhibitors is...
8.
Kulkarni A, Drake J, Armstrong D, Dirks P
J Neurosurg
. 2000 Jun;
92(6):915-9.
PMID: 10839249
Object: The goal of this study was to determine and compare imaging correlates in pediatric patients who underwent successful or failed endoscopic third ventriculostomies (ETVs). To this end, the authors...
9.
Kulkarni A, Drake J, Armstrong D, Dirks P
Pediatr Neurosurg
. 1999 Dec;
31(2):65-70.
PMID: 10592474
Introduction: The frontal and occipital horn ration (FOR) has recently been described as a simple, linear measurement of ventricular size that correlates very well with ventricular volume. This study further...
10.
Rutka J, Muller M, Hubbard S, Forsdike J, Dirks P, Jung S, et al.
J Neuropathol Exp Neurol
. 1999 Feb;
58(2):198-209.
PMID: 10029102
Evidence is accumulating implicating a role for integrins in the pathogenesis of cancer, a disease in which alterations in cellular growth, differentiation, and adhesive characteristics are defining features. In the...