P Andy Futreal
Overview
Explore the profile of P Andy Futreal including associated specialties, affiliations and a list of published articles.
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5
Citations
377
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0
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Recent Articles
1.
Lu T, Park S, Han Y, Wang Y, Hubert S, Futreal P, et al.
Nat Methods
. 2022 Oct;
19(11):1480-1489.
PMID: 36303017
Neoantigens are the key targets of antitumor immune responses from cytotoxic T cells and play a critical role in affecting tumor progressions and immunotherapy treatment responses. However, little is known...
2.
Yen J, White R, Wedge D, Van Loo P, de Ridder J, Capper A, et al.
Genome Biol
. 2013 Oct;
14(10):R113.
PMID: 24148783
Background: Melanoma is the most deadly form of skin cancer. Expression of oncogenic BRAF or NRAS, which are frequently mutated in human melanomas, promote the formation of nevi but are...
3.
Mattison J, Kool J, Uren A, de Ridder J, Wessels L, Jonkers J, et al.
Cancer Res
. 2010 Jan;
70(3):883-95.
PMID: 20103622
Comparative genomic hybridization (CGH) can reveal important disease genes but the large regions identified could sometimes contain hundreds of genes. Here we combine high-resolution CGH analysis of 598 human cancer...
4.
Greenman C, Bignell G, Butler A, Edkins S, Hinton J, Beare D, et al.
Biostatistics
. 2009 Oct;
11(1):164-75.
PMID: 19837654
High-throughput oligonucleotide microarrays are commonly employed to investigate genetic disease, including cancer. The algorithms employed to extract genotypes and copy number variation function optimally for diploid genomes usually associated with...
5.
Campbell P, Pleasance E, Stephens P, Dicks E, Rance R, Goodhead I, et al.
Proc Natl Acad Sci U S A
. 2008 Aug;
105(35):13081-6.
PMID: 18723673
During the clonal expansion of cancer from an ancestral cell with an initiating oncogenic mutation to symptomatic neoplasm, the occurrence of somatic mutations (both driver and passenger) can be used...