P A Craven
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Explore the profile of P A Craven including associated specialties, affiliations and a list of published articles.
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Articles
110
Citations
949
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Recent Articles
1.
Craven P, Rycroft M
Adv Space Res
. 2005 Jun;
35(2):300-4.
PMID: 15934210
Amongst the great variety of heavy particles present in the galactic and solar cosmic ray spectra, hydrogen and helium nuclei are significantly more abundant than all other heavier ions and,...
2.
Craven P, Phillips S, Melhem M, Liachenko J, Derubertis F
Metabolism
. 2001 Sep;
50(9):1043-8.
PMID: 11555836
Superoxide has been implicated in the cellular signalling pathways, which regulate growth of mesangial cells (MC) and vascular smooth muscle cells. Manganese (Mn)(2+)-dependent superoxide dismutase (SOD-2) is primarily responsible for...
3.
Craven P, Melhem M, Phillips S, Derubertis F
Diabetes
. 2001 Aug;
50(9):2114-25.
PMID: 11522679
Ex vivo and in vitro observations implicate superoxide as a mediator of cell injury in diabetes, but in vivo evidence is lacking. In the current studies, parameters of glomerular injury...
4.
Phillips S, Derubertis F, Craven P
Diabetes
. 1999 Oct;
48(10):2083-9.
PMID: 10512377
Expression of the genes encoding several matrix proteins, including the laminin gamma1 and beta1 subunits, is increased in glomeruli or renal cortex from diabetic animals or in mesangial cells cultured...
5.
Craven P, Derubertis F, Kagan V, Melhem M, Studer R
J Am Soc Nephrol
. 1997 Sep;
8(9):1405-14.
PMID: 9294832
Oxidant stress and a reduction in antioxidant status, including reduced plasma and tissue ascorbic acid content, occur in diabetic patients and experimental models of diabetes. In this study, the effects...
6.
Craven P, Derubertis F, Melhem M
Kidney Int Suppl
. 1997 Sep;
60:S46-53.
PMID: 9285902
No abstract available.
7.
Studer R, Craven P, Derubertis F
Metabolism
. 1997 Aug;
46(8):918-25.
PMID: 9258275
Protein kinase C (PKC)-signaled increases in transforming growth factor beta (TGF beta) have been implicated in the stimulation of matrix protein synthesis induced by high concentrations of glucose, thromboxane, angiotension...
8.
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells
Craven P, Studer R, Felder J, Phillips S, Derubertis F
Diabetes
. 1997 Apr;
46(4):671-81.
PMID: 9075810
Culture of mesangial cells (MCs) in 5.6 vs. 30.0 mmol/l glucose for 3 weeks induced a sustained increase in protein kinase C (PKC) activity, transforming growth factor (TGF)-beta1 mRNA, bioactive...
9.
Craven P, Studer R, Derubertis F
Hypertension
. 1996 Aug;
28(2):169-76.
PMID: 8707377
In the present study, we examined the effect of the thromboxane/prostaglandin endoperoxide analogue U46619 on proliferation and hypertrophy in cultured rat vascular smooth muscle cells and the roles of protein...
10.
Studer R, Derubertis F, Craven P
J Am Soc Nephrol
. 1996 Jul;
7(7):999-1005.
PMID: 8829114
Thromboxane (TX) stimulation of fibronectin (FN) synthesis in mesangial cells (MC) is dependent on protein kinase C (PKC)-mediated increases in transforming growth factor beta (TGF beta), and is suppressed by...