Owen J L Rackham
Overview
Explore the profile of Owen J L Rackham including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
54
Citations
4083
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cull J, Cooper S, Alharbi H, Chothani S, Rackham O, Meijles D, et al.
Clin Sci (Lond)
. 2024 May;
138(10):573-597.
PMID: 38718356
The three striatins (STRN, STRN3, STRN4) form the core of STRiatin-Interacting Phosphatase and Kinase (STRIPAK) complexes. These place protein phosphatase 2A (PP2A) in proximity to protein kinases thereby restraining kinase...
2.
Wieder N, DSouza E, Martin-Geary A, Lassen F, Talbot-Martin J, Fernandes M, et al.
Genome Biol
. 2024 Apr;
25(1):111.
PMID: 38685090
Background: Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but...
3.
Buckberry S, Liu X, Poppe D, Tan J, Sun G, Chen J, et al.
Nature
. 2023 Aug;
620(7975):863-872.
PMID: 37587336
Cells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly,...
4.
Quah H, Cao E, Suteja L, Li C, Leong H, Chong F, et al.
Nat Commun
. 2023 Mar;
14(1):1680.
PMID: 36973261
Profiling tumors at single-cell resolution provides an opportunity to understand complexities underpinning lymph-node metastases in head and neck squamous-cell carcinoma. Single-cell RNAseq (scRNAseq) analysis of cancer-cell trajectories identifies a subpopulation...
5.
Ouyang J, Chothani S, Rackham O
Stem Cell Reports
. 2023 Jan;
18(1):6-12.
PMID: 36630908
Our ability to understand and control stem cell biology is being augmented by developments on two fronts, our ability to collect more data describing cell state and our capability to...
6.
Lee L, Christodoulou E, Shyamsunder P, Jun Chen B, Lee K, Kan Fung T, et al.
Oncogene
. 2022 Oct;
41(48):5160-5175.
PMID: 36271030
Acute myeloid leukaemia (AML) is a rapidly fatal blood cancer that is characterised by the accumulation of immature myeloid cells in the blood and bone marrow as a result of...
7.
Chothani S, Adami E, Widjaja A, Langley S, Viswanathan S, Pua C, et al.
Mol Cell
. 2022 Jul;
82(15):2885-2899.e8.
PMID: 35841888
Translated small open reading frames (smORFs) can have important regulatory roles and encode microproteins, yet their genome-wide identification has been challenging. We determined the ribosome locations across six primary human...
8.
Marshall J, Cull J, Alharbi H, Zaw Thin M, Cooper S, Barrington C, et al.
Biochem J
. 2022 Jun;
479(13):1467-1486.
PMID: 35730579
The protein kinase PKN2 is required for embryonic development and PKN2 knockout mice die as a result of failure in the expansion of mesoderm, cardiac development and neural tube closure....
9.
Nefzger C, Jarde T, Srivastava A, Schroeder J, Rossello F, Horvay K, et al.
NPJ Regen Med
. 2022 Jun;
7(1):31.
PMID: 35710627
The impact of aging on intestinal stem cells (ISCs) has not been fully elucidated. In this study, we identified widespread epigenetic and transcriptional alterations in old ISCs. Using a reprogramming...
10.
Kerouanton B, Schafer S, Ho L, Chothani S, Rackham O
Bioinformatics
. 2022 Jun;
38(14):3651-3653.
PMID: 35652722
Motivation: The creation and analysis of gene regulatory networks have been the focus of bioinformatics research and underpins much of what is known about gene regulation. However, as a result...