Owen G James
Overview
Explore the profile of Owen G James including associated specialties, affiliations and a list of published articles.
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11
Citations
120
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Recent Articles
1.
Banerjee P, Mehta A, Nirujogi R, Cooper J, James O, Nanda J, et al.
Sci Adv
. 2023 Apr;
9(16):eabq0651.
PMID: 37083530
Although microglial activation is widely found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), the underlying mechanism(s) are poorly understood. Here, using human-induced pluripotent stem cell-derived microglia-like cells (hiPSC-MG)...
2.
Barton S, Magnani D, James O, Livesey M, Selvaraj B, James O, et al.
Brain Commun
. 2022 Mar;
3(4):fcab255.
PMID: 35350711
Oligodendrocytes are implicated in amyotrophic lateral sclerosis pathogenesis and display transactive response DNA-binding protein-43 (TDP-43) pathological inclusions. To investigate the cell autonomous consequences of TDP-43 mutations on human oligodendrocytes, we...
3.
James O, Selvaraj B, Magnani D, Burr K, Connick P, Barton S, et al.
Dev Cell
. 2022 Jan;
57(1):146.
PMID: 35016003
No abstract available.
4.
Barton S, Gregory J, Selvaraj B, McDade K, Henstridge C, Spires-Jones T, et al.
Front Neurosci
. 2021 Sep;
15:705306.
PMID: 34539336
Pathological hallmarks of amyotrophic lateral sclerosis (ALS), including protein misfolding, are well established in oligodendrocytes. More recently, an RNA trafficking deficit of key myelin proteins has been suggested in oligodendrocytes...
5.
James O, Mehta A, Behari M, Chandran S
Lancet Neurol
. 2021 May;
20(6):422.
PMID: 34022167
No abstract available.
6.
James O, Selvaraj B, Magnani D, Burr K, Connick P, Barton S, et al.
Dev Cell
. 2021 May;
56(9):1346-1358.e6.
PMID: 33945785
Myelination is essential for central nervous system (CNS) formation, health, and function. Emerging evidence of oligodendrocyte heterogeneity in health and disease and divergent CNS gene expression profiles between mice and...
7.
Banerjee P, Paza E, Perkins E, James O, Kenkhuis B, Lloyd A, et al.
Stem Cell Res
. 2020 Oct;
49:102046.
PMID: 33096385
Microglia are resident tissue macrophages of the central nervous system (CNS) that arise from erythromyeloid progenitors during embryonic development. They play essential roles in CNS development, homeostasis and response to...
8.
DSouza M, Gowda N, Tiwari V, Ottakandathil Babu R, Anand P, Ghosh Dastidar S, et al.
iScience
. 2019 Feb;
12:368.
PMID: 30763793
No abstract available.
9.
Harkin L, Lindsay S, Xu Y, Alzubi A, Ferrera A, Gullon E, et al.
Cereb Cortex
. 2019 Feb;
29(4):1705.
PMID: 30753338
No abstract available.
10.
DSouza M, Gowda N, Tiwari V, Ottakandathil Babu R, Anand P, Ghosh Dastidar S, et al.
iScience
. 2018 Nov;
9:399-411.
PMID: 30469012
FMRP is an RNA-binding protein that is known to localize in the cytoplasm and in the nucleus. Here, we have identified an interaction of FMRP with a specific set of...