Otto Holbrook
Overview
Explore the profile of Otto Holbrook including associated specialties, affiliations and a list of published articles.
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2
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Recent Articles
1.
Gardner Z, Holbrook O, Tian Y, Odamah K, Man H
Exp Neurol
. 2024 Mar;
376:114756.
PMID: 38508482
Overexpression of the Ube3a gene and the resulting increase in Ube3a protein are linked to autism spectrum disorder (ASD). However, the cellular and molecular processes underlying Ube3a-dependent ASD remain unclear....
2.
McGlynn R, Cui M, Brems B, Holbrook O, Booth R
ACS Chem Neurosci
. 2023 Dec;
15(2):357-370.
PMID: 38150333
The serotonin (5-hydroxytryptamine, 5-HT) 5-HT G-protein coupled receptor subtypes (5-HT) share a high sequence homology, confounding development of subtype-specific ligands. This study used a 5-HT structure-based ligand design approach to...