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Oskar Karlsson

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Articles 73
Citations 981
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Recent Articles
1.
Theodoropoulou E, Pierozan P, Marabita F, Hoglund A, Karlsson O
Chemosphere . 2024 Oct; 368:143605. PMID: 39442571
The environmental contaminant dibutyl phthalate (DBP) is reported to be hepatotoxic, but the underlying molecular pathways and pathological processes remain unclear. Here we used RNA-sequencing to characterize persistent hepatic transcriptional...
2.
Stordal B, Harvie M, Antoniou M, Bellingham M, Chan D, Darbre P, et al.
Cancer Med . 2024 Sep; 13(18):e70255. PMID: 39315735
The Breast Cancer UK-Breast Cancer Prevention Conference addressed risk from environmental pollutants and health behaviour-related breast-cancer risk. Epidemiological studies examining individual chemicals and breast cancer risk have produced inconclusive results...
3.
Strand D, Lundgren B, Bergdahl I, Martin J, Karlsson O
Environ Int . 2024 Sep; 192:108991. PMID: 39299052
Chemical risk assessments typically focus on single substances, often overlooking real-world co-exposures to chemical mixtures. Mixture toxicology studies using representative mixtures can reveal potential chemical interactions, but these do not...
4.
Abele C, Perez A, Hoglund A, Pierozan P, Breitholtz M, Karlsson O
Environ Sci Technol . 2024 Aug; 58(36):15926-15937. PMID: 39190186
This study demonstrated the strengths of in vivo molecular staining coupled with automated imaging analysis in . A multiwell plate protocol was developed to assess mitochondrial membrane potential using the...
5.
Roza M, Eriksson A, Svanholm S, Berg C, Karlsson O
J Hazard Mater . 2024 Aug; 478:135455. PMID: 39154485
The unsustainable use of manmade chemicals poses significant threats to biodiversity and human health. Emerging evidence highlights the potential of certain chemicals to cause transgenerational impacts on metabolic health. Here,...
6.
Strand D, Nylander E, Hoglund A, Lundgren B, Martin J, Karlsson O
Cell Biol Toxicol . 2024 Aug; 40(1):69. PMID: 39136868
Many persistent organic pollutants (POPs) are suspected endocrine disruptors and it is important to investigate their effects at low concentrations relevant to human exposure. Here, the OECD test guideline #456...
7.
Pierozan P, Hoglund A, Theodoropoulou E, Karlsson O
Sci Total Environ . 2024 Jul; 949:174864. PMID: 39032741
DNA methylation plays a pivotal role in cancer. The ubiquitous contaminant perfluorooctanesulfonic acid (PFOS) has been epidemiologically associated with breast cancer, and can induce proliferation and malignant transformation of normal...
8.
Almamoun R, Pierozan P, Karlsson O
Arch Toxicol . 2024 May; 98(8):2695-2709. PMID: 38769170
To improve the mechanistic screening of reproductive toxicants in  chemical-risk assessment and drug development, we have developed a three-dimensional (3D) heterogenous testicular co-culture model from neonatal mice. Di-n-butyl phthalate (DBP),...
9.
Roza M, Eriksson A, Svanholm S, Berg C, Karlsson O
Sci Total Environ . 2024 Feb; 923:170949. PMID: 38365020
The herbicide linuron can cause endocrine disrupting effects in Xenopus tropicalis frogs, including offspring that were never exposed to the contaminant. The mechanisms by which these effects are transmitted across...
10.
Bui T, Aasa J, Abass K, Agerstrand M, Beronius A, Castro M, et al.
Environ Sci Process Impacts . 2024 Jan; 26(2):380-399. PMID: 38205707
This work presents a case study in applying a systematic review framework (SYRINA) to the identification of chemicals as endocrine disruptors. The suitability and performance of the framework is tested...