Oskar Hoffmann
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Explore the profile of Oskar Hoffmann including associated specialties, affiliations and a list of published articles.
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22
Citations
628
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Recent Articles
11.
Binder N, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig T, et al.
Nat Med
. 2009 Mar;
15(4):417-24.
PMID: 19330010
Understanding the mechanisms of osteoclastogenesis is crucial for developing new drugs to treat diseases associated with bone loss, such as osteoporosis. Here we report that the C-C chemokine receptor-2 (CCR2)...
12.
Seckinger J, Sommerer C, Hinkel U, Hoffmann O, Zeier M, Schwenger V
J Hypertens
. 2008 Oct;
26(11):2213-9.
PMID: 18854763
Background: Cardiovascular mortality is extraordinarily high in renal allograft recipients and accounts for almost half of all allograft losses. Whereas the immunosuppression with calcineurin inhibitors is associated with an increased...
13.
Stolz E, Fox B, Hoffmann O, Gerriets T, Blaes F, Kraus J, et al.
J Neuroimaging
. 2008 Sep;
19(1):31-6.
PMID: 18798778
Background: Although there exists a large body of knowledge on the regulation of arterial cerebral hemodynamics, little is known about the cerebral venous outflow (CVO). Methods: In 19 healthy volunteers,...
14.
Manetti F, Santucci A, Locatelli G, Maga G, Spreafico A, Serchi T, et al.
J Med Chem
. 2007 Oct;
50(23):5579-88.
PMID: 17929792
New pyrazolo[3,4-d]pyrimidines were synthesized and found to inhibit Src phosphorylation in a cell-free assay. Some of them significantly reduced the growth of human osteogenic sarcoma (SaOS-2) cells. The best compound,...
15.
Zwerina J, Redlich K, Polzer K, Joosten L, Kronke G, Distler J, et al.
Proc Natl Acad Sci U S A
. 2007 Jul;
104(28):11742-7.
PMID: 17609389
Blocking TNF effectively inhibits inflammation and structural damage in human rheumatoid arthritis (RA). However, so far it is unclear whether the effect of TNF is a direct one or indirect...
16.
Toegel S, Hoffmann O, Wadsak W, Ettlinger D, Mien L, Wiesner K, et al.
Eur J Nucl Med Mol Imaging
. 2006 Jan;
33(4):491-4.
PMID: 16416330
Purpose: Although polyphosphonates (PPs) were introduced as bone imaging agents in nuclear medicine in the early 1970s, the mechanisms involved in their uptake still remain unclear. Suggested mechanisms range from...
17.
Schwenger V, Morath C, Hofmann A, Hoffmann O, Zeier M, Ritz E
Nephrol Dial Transplant
. 2006 Jan;
21(4):962-7.
PMID: 16396974
Background: The population of incident dialysis patients is progressively ageing and dialysis outcome is particularly poor in the elderly. There is little documentation whether late referral is more frequent in...
18.
Zwerina J, Tzima S, Hayer S, Redlich K, Hoffmann O, Hanslik-Schnabel B, et al.
FASEB J
. 2005 Oct;
19(14):2011-3.
PMID: 16234431
Heme oxygenase 1 (HO-1) plays an important role in vascular disease, transplantation, and inflammation. In animal models of acute and chronic inflammation, induction of HO-1 has anti-inflammatory and cytoprotective properties....
19.
Kluger R, Muhlberger H, Hoffmann O, Berger C, Engel A, Pavlova B
Clin Orthop Relat Res
. 2005 Apr;
(433):251-7.
PMID: 15805965
The goal of this study was to determine whether human osteoblasts might harbor the hepatitis C virus. We tested for positive-strand and negative-strand (replicative) hepatitis C virus RNA by reverse...
20.
Hayer S, Steiner G, Gortz B, Reiter E, Tohidast-Akrad M, Amling M, et al.
J Exp Med
. 2005 Mar;
201(6):903-14.
PMID: 15781582
Chronic inflammation is a major trigger of local and systemic bone loss. Disintegration of cell-matrix interaction is a prerequisite for the invasion of inflammatory tissue into bone. CD44 is a...