Oscar Suzuki
Overview
Explore the profile of Oscar Suzuki including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
142
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0
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Recent Articles
1.
Zhu J, Campagne O, Torrice C, Flynn G, Miller J, Patel T, et al.
Clin Transl Sci
. 2021 Jan;
14(3):908-918.
PMID: 33502111
Tacrolimus is a calcineurin inhibitor used to prevent acute graft versus host disease in adult patients receiving allogeneic hematopoietic stem cell transplantation (HCT). Previous population pharmacokinetic (PK) models have been...
2.
Zhu J, Patel T, Miller J, Torrice C, Aggarwal M, Sketch M, et al.
Int J Mol Sci
. 2020 Feb;
21(3).
PMID: 32013193
Tacrolimus exhibits high inter-patient pharmacokinetics (PK) variability, as well as a narrow therapeutic index, and therefore requires therapeutic drug monitoring. Germline mutations in cytochrome P450 isoforms 4 and 5 genes...
3.
Suzuki O, Dong O, Howard R, Wiltshire T
Pharmacogenomics
. 2019 Sep;
20(14):1005-1020.
PMID: 31559919
This study assesses the technical performance and cost of a targeted next-generation sequencing (NGS) multigene pharmacogenetic (PGx) test. A genetic test was developed for 21 PGx genes using molecular inversion...
4.
Frick A, Benton C, Suzuki O, Dong O, Howard R, El-Sabae H, et al.
Pharmacy (Basel)
. 2018 Oct;
6(4).
PMID: 30360487
Pharmacogenomics provides a personalized approach to pharmacotherapy by using genetic information to guide drug dosing and selection. However, partly due to lack of education, pharmacogenomic testing has not been fully...
5.
Dong O, Li A, Suzuki O, Oni-Orisan A, Gonzalez R, Stouffer G, et al.
Pharmacogenomics
. 2018 May;
19(9):771-782.
PMID: 29793377
Aim: To determine the projected impact of a multigene pharmacogenetic (PGx) test on medication prescribing. Materials & Methods: A retrospective analysis was conducted with 122 cardiac catheterization laboratory patients undergoing...
6.
Chen J, Akhtari F, Wagner M, Suzuki O, Wiltshire T, Motsinger-Reif A, et al.
Clin Transl Sci
. 2017 Dec;
11(2):226-236.
PMID: 29205871
Analysis of aging and pharmacogenetics (PGx) on antiretroviral pharmacokinetics (PKs) could inform precision dosing for older human HIV-infected patients. Seventy-four participants receiving either atazanavir/ritonavir (ATV/RTV) or efavirenz (EFV) with tenofovir/emtricitabine...
7.
High M, Cho H, Marzec J, Wiltshire T, Verhein K, Caballero M, et al.
EBioMedicine
. 2016 Aug;
11:73-84.
PMID: 27554839
Background: Respiratory syncytial virus (RSV) is the global leading cause of lower respiratory tract infection in infants. Nearly 30% of all infected infants develop severe disease including bronchiolitis, but susceptibility...
8.
Frick A, Fedoriw Y, Richards K, Damania B, Parks B, Suzuki O, et al.
Pharmgenomics Pers Med
. 2015 Apr;
8:81-98.
PMID: 25897258
Background: Interpatient variability in immune and chemotherapeutic cytotoxic responses is likely due to complex genetic differences and is difficult to ascertain in humans. Through the use of a panel of...
9.
Nichols J, Gladwell W, Verhein K, Cho H, Wess J, Suzuki O, et al.
FASEB J
. 2014 Feb;
28(6):2538-50.
PMID: 24571919
Reactive oxygen species (ROS) contribute to the pathogenesis of many acute and chronic pulmonary disorders, including bronchopulmonary dysplasia (BPD), a respiratory condition that affects preterm infants. However, the mechanisms of...
10.
Frick A, Suzuki O, Butz N, Chan E, Wiltshire T
Methods Mol Biol
. 2013 Jul;
1015:263-78.
PMID: 23824862
The identification of causative genes underlying biomedically relevant phenotypes, particularly complex multigenic traits, is of vital interest to modern medicine. Using genome-wide association analysis, many studies have successfully identified thousands...