Ori Avinoam
Overview
Explore the profile of Ori Avinoam including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1268
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0
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Recent Articles
1.
Kamalesh K, Segal D, Avinoam O, Schejter E, Shilo B
J Cell Sci
. 2024 Jun;
137(13).
PMID: 38899547
The Rho family of GTPases plays a crucial role in cellular mechanics by regulating actomyosin contractility through the parallel induction of actin and myosin assembly and function. Using exocytosis of...
2.
Khan S, Partuk E, Chiaravalli J, Kozer N, Shurrush K, Elbaz-Alon Y, et al.
iScience
. 2024 Jun;
27(6):110019.
PMID: 38883823
The COVID-19 pandemic highlighted the need for antivirals against emerging coronaviruses (CoV). Inhibiting spike (S) glycoprotein-mediated viral entry is a promising strategy. To identify small molecule inhibitors that block entry...
3.
Shakarchy A, Zarfati G, Hazak A, Mealem R, Huk K, Ziv T, et al.
Mol Syst Biol
. 2024 Jan;
20(3):217-241.
PMID: 38238594
Cells modify their internal organization during continuous state transitions, supporting functions from cell division to differentiation. However, tools to measure dynamic physiological states of individual transitioning cells are lacking. We...
4.
Biton T, Scher N, Carmon S, Elbaz-Alon Y, Schejter E, Shilo B, et al.
J Cell Biol
. 2023 Sep;
222(11).
PMID: 37707500
Exocrine cells utilize large secretory vesicles (LSVs) up to 10 μm in diameter. LSVs fuse with the apical surface, often recruiting actomyosin to extrude their content through dynamic fusion pores....
5.
Mund M, Tschanz A, Wu Y, Frey F, Mehl J, Kaksonen M, et al.
J Cell Biol
. 2023 Feb;
222(3).
PMID: 36734980
Eukaryotic cells use clathrin-mediated endocytosis to take up a large range of extracellular cargo. During endocytosis, a clathrin coat forms on the plasma membrane, but it remains controversial when and...
6.
Morandi M, Busko P, Ozer-Partuk E, Khan S, Zarfati G, Elbaz-Alon Y, et al.
PNAS Nexus
. 2023 Jan;
1(4):pgac156.
PMID: 36714848
Extracellular vesicles (EVs) transfer bioactive molecules between cells in a process reminiscent of enveloped viruses. EV cargo delivery is thought to occur by protein-mediated and pH-dependent membrane fusion of the...
7.
Kluzek M, Oppenheimer-Shaanan Y, Dadosh T, Morandi M, Avinoam O, Raanan C, et al.
ACS Nano
. 2022 Aug;
16(10):15792-15804.
PMID: 36018573
Drug delivery via nanovehicles is successfully employed in several clinical settings, yet bacterial infections, forming microbial communities in the form of biofilms, present a strong challenge to therapeutic treatment due...
8.
Galisova A, Zahradnik J, Allouche-Arnon H, Morandi M, Karam P, Fisler M, et al.
ACS Nano
. 2022 Aug;
16(8):12276-12289.
PMID: 35921522
The elucidation of viral-receptor interactions and an understanding of virus-spreading mechanisms are of great importance, particularly in the era of a pandemic. Indeed, advances in computational chemistry, synthetic biology, and...
9.
Sinha S, Elbaz-Alon Y, Avinoam O
FEBS J
. 2022 Jun;
289(21):6531-6542.
PMID: 35689496
Muscle regeneration is essential for vertebrate muscle homeostasis and recovery after injury. During regeneration, muscle stem cells differentiate into myocytes, which then fuse with pre-existing muscle fibres. Hence, differentiation, fusion...
10.
Karam P, Rosenhek-Goldian I, Ziv T, Ben Ami Pilo H, Azuri I, Rivkin A, et al.
EMBO Rep
. 2022 Jun;
23(7):e54755.
PMID: 35642585
Malaria is the most serious mosquito-borne parasitic disease, caused mainly by the intracellular parasite Plasmodium falciparum. The parasite invades human red blood cells and releases extracellular vesicles (EVs) to alter...