Orchidee Filipe-Santos
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Explore the profile of Orchidee Filipe-Santos including associated specialties, affiliations and a list of published articles.
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1567
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Recent Articles
1.
Berteau C, Filipe-Santos O, Wang T, Rojas H, Granger C, Schwarzenbach F
Med Devices (Auckl)
. 2015 Dec;
8:473-84.
PMID: 26635489
Aim: The primary objective of this study was to evaluate the impact of fluid injection viscosity in combination with different injection volumes and flow rates on subcutaneous (SC) injection pain...
2.
Prando C, Samarina A, Bustamante J, Boisson-Dupuis S, Cobat A, Picard C, et al.
Medicine (Baltimore)
. 2013 Feb;
92(2):109-122.
PMID: 23429356
Autosomal recessive interleukin (IL)-12 p40 (IL-12p40) deficiency is a rare genetic etiology of mendelian susceptibility to mycobacterial disease (MSMD). We report the genetic, immunologic, and clinical features of 49 patients...
3.
Venet F, Filipe-Santos O, Lepape A, Malcus C, Poitevin-Later F, Grives A, et al.
Crit Care Med
. 2012 Dec;
41(1):111-9.
PMID: 23222261
Objective: Septic syndromes are the leading causes of mortality in intensive care units. In patients, the occurrence of sepsis-induced immune suppression is associated with delayed mortality, although the exact role...
4.
Muller A, Filipe-Santos O, Eberl G, Aebischer T, Spath G, Bousso P
Immunity
. 2012 Jun;
37(1):147-57.
PMID: 22727490
Effector T cells are critical for clearance of pathogens from sites of infection. Like cytotoxic CD8(+) T cells, CD4(+) helper T cells have been shown to deliver effector molecules directionally...
5.
Grant A, Boisson-Dupuis S, Herquelot E, de Beaucoudrey L, Filipe-Santos O, Nolan D, et al.
J Med Genet
. 2011 May;
48(8):567-71.
PMID: 21572128
Introduction: Genome-wide homozygosity mapping is a powerful method for locating rare recessive Mendelian mutations. However, statistical power decreases dramatically in the presence of genetic heterogeneity. Methods: The authors applied an...
6.
de Beaucoudrey L, Samarina A, Bustamante J, Cobat A, Boisson-Dupuis S, Feinberg J, et al.
Medicine (Baltimore)
. 2010 Nov;
89(6):381-402.
PMID: 21057261
Interleukin-12 receptor β1 (IL-12Rβ1) deficiency is the most common form of Mendelian susceptibility to mycobacterial disease (MSMD). We undertook an international survey of 141 patients from 102 kindreds in 30...
7.
Filipe-Santos O, Pescher P, Breart B, Lippuner C, Aebischer T, Glaichenhaus N, et al.
Cell Host Microbe
. 2009 Jul;
6(1):23-33.
PMID: 19616763
CD4 T helper cells play a central role in the control of infection by intracellular parasites. How efficiently pathogen-specific CD4 T cells detect infected cells in vivo is unclear. Here,...
8.
de Beaucoudrey L, Puel A, Filipe-Santos O, Cobat A, Ghandil P, Chrabieh M, et al.
J Exp Med
. 2008 Jul;
205(7):1543-50.
PMID: 18591412
The cytokines controlling the development of human interleukin (IL) 17--producing T helper cells in vitro have been difficult to identify. We addressed the question of the development of human IL-17--producing...
9.
Guia S, Cognet C, de Beaucoudrey L, Tessmer M, Jouanguy E, Berger C, et al.
Blood
. 2008 Mar;
111(10):5008-16.
PMID: 18319400
Natural killer (NK) cells have been originally defined by their "naturally occurring" effector function. However, only a fraction of human NK cells is reactive toward a panel of prototypical tumor...
10.
Bustamante J, Aksu G, Vogt G, de Beaucoudrey L, Genel F, Chapgier A, et al.
J Allergy Clin Immunol
. 2007 Jun;
120(1):32-8.
PMID: 17544093
A few known primary immunodeficiencies confer predisposition to clinical disease caused by weakly virulent mycobacteria, such as BCG vaccines (regional disease, known as BCG-itis, or disseminated disease, known as BCG-osis),...