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Onat Kadioglu

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Articles 59
Citations 887
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Recent Articles
21.
Efferth T, Saeed M, Kadioglu O, Seo E, Shirooie S, Mbaveng A, et al.
Biotechnol Adv . 2019 Feb; 38:107342. PMID: 30708024
Cancer chemotherapy is frequently hampered by drug resistance. Concepts to combine anticancer drugs with different modes of action to avoid the development of resistance did not provide the expected success...
22.
Mitani Y, Satake K, Tsukamoto M, Nakamura I, Kadioglu O, Teruya T, et al.
Phytomedicine . 2018 Nov; 51:112-119. PMID: 30466608
Background: Epimagnolin A is an ingredient of the Chinese crude drug Shin-i, derived from the dried flower buds of Magnolia fargesii and Magnolia flos, which has been traditionally used for...
23.
Efferth T, Banerjee M, Abu-Darwish M, Abdelfatah S, Bockers M, Bhakta-Guha D, et al.
Phytomedicine . 2018 Sep; 53:319-331. PMID: 30190231
Background: Practices of biopiracy to use genetic resources and indigenous knowledge by Western companies without benefit-sharing of those, who generated the traditional knowledge, can be understood as form of neocolonialism....
24.
Sachs J, Kadioglu O, Weber A, Mundorf V, Betz J, Efferth T, et al.
J Nat Med . 2018 Aug; 73(1):226-235. PMID: 30066239
Overexpression of efflux transporters of the ATP-binding cassette (ABC) transporter family, primarily P-glycoprotein (P-gp), is a frequent cause of multidrug resistance in cancer and leads to failure of current chemotherapies....
25.
Kadioglu O, Saeed M, Kuete V, Greten H, Efferth T
Front Pharmacol . 2018 May; 9:355. PMID: 29713280
Drug resistance is one of the main reasons of chemotherapy failure. Therefore, overcoming drug resistance is an invaluable approach to identify novel anticancer drugs that have the potential to bypass...
26.
Kadioglu O, Chan A, Ling Qiu A, Wong V, Colligs V, Wecklein S, et al.
Front Pharmacol . 2017 Oct; 8:711. PMID: 29062278
DNA topoisomerases 1 and 2 are enzymes that maintain DNA topology and play important essential genome functions, including DNA replication and transcription. Aberrant topoisomerases cause genome instability and a wide...
27.
Hong C, Cao J, Wu C, Kadioglu O, Schuffler A, Kauhl U, et al.
Sci Rep . 2017 Sep; 7(1):11551. PMID: 28912423
Posttraumatic stress disorder (PTSD) gains a lot of attention due to high prevalence and strong psychological upset, but the etiology remains undefined and effective treatment is quite limited. Growing studies...
28.
Kadioglu O, Law B, Mok S, Xu S, Efferth T, Wong V
Front Pharmacol . 2017 May; 8:238. PMID: 28529482
Neferine, a bisbenzylisoquinoline alkaloid isolated from the green seed embryos of Lotus ( Gaertn), has been previously shown to have various anti-cancer effects. In the present study, we evaluated the...
29.
To K, Wu X, Yin C, Chai S, Yao S, Kadioglu O, et al.
J Ethnopharmacol . 2017 Apr; 203:110-119. PMID: 28363522
Ethnopharmacological Relevance: Multidrug resistance (MDR) of cancer is often associated with the overexpression of ATP-binding cassette (ABC) transporters, such as P-glycoprotein (P-gp), multidrug resistance-associated protein-1 (MRP-1) and breast cancer resistance...
30.
Colligs V, Hansen S, Imbri D, Seo E, Kadioglu O, Efferth T, et al.
Bioorg Med Chem . 2017 Feb; 25(22):6137-6148. PMID: 28233677
A D-ring contracted analogue of the strongly cytotoxic marine pyrrole alkaloid lamellarin D was synthesized and investigated for its antiproliferative action towards a wild type and a multidrug resistant (MDR)...