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Omer Adir

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Articles 11
Citations 581
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Recent Articles
1.
Melamed M, Asraf H, Livne N, Bogdanovic M, Shendge A, Shamir G, et al.
iScience . 2025 Feb; 28(2):111912. PMID: 40017509
Reduced saliva secretion, dry mouth, and loss of taste are debilitating symptoms associated with zinc deficiency. A mechanism for zinc regulation of these processes is lacking. Here, we identified the...
2.
Sela M, Poley M, Mora-Raimundo P, Kagan S, Avital A, Kaduri M, et al.
Adv Mater . 2023 Sep; 35(51):e2304654. PMID: 37753928
Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although poor delivery to the brain hinders their therapeutic application. In the current study, it is demonstrated that brain-targeted liposomes...
3.
Chen G, Levin R, Landau S, Kaduri M, Adir O, Ianovici I, et al.
Proc Natl Acad Sci U S A . 2022 Sep; 119(38):e2207525119. PMID: 36095208
Progress in bottom-up synthetic biology has stimulated the development of synthetic cells (SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing diseased natural cells and addressing medical needs. Here, we...
4.
Adir O, Albalak M, Abel R, Weiss L, Chen G, Gruber A, et al.
Nat Commun . 2022 Apr; 13(1):2328. PMID: 35484097
Development of regulated cellular processes and signaling methods in synthetic cells is essential for their integration with living materials. Light is an attractive tool to achieve this, but the limited...
5.
Mendes B, Conniot J, Avital A, Yao D, Jiang X, Zhou X, et al.
Nat Rev Methods Primers . 2022 Apr; 2. PMID: 35480987
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented opportunity to overcome these...
6.
Poley M, Mora-Raimundo P, Shammai Y, Kaduri M, Koren L, Adir O, et al.
ACS Nano . 2022 Mar; 16(4):5246-5257. PMID: 35293714
Throughout the female menstrual cycle, physiological changes occur that affect the biodistribution of nanoparticles within the reproductive system. We demonstrate a 2-fold increase in nanoparticle accumulation in murine ovaries and...
7.
Adir O, Sharf-Pauker N, Chen G, Kaduri M, Krinsky N, Shainsky-Roitman J, et al.
J Vis Exp . 2020 May; (158). PMID: 32391815
The bottom-up assembly approach for construction of synthetic cells is an effective tool for isolating and investigating cellular processes in a cell mimicking environment. Furthermore, the development of cell-free expression...
8.
Weiss L, Shalev Ezra Y, Goldberg S, Ferdman B, Adir O, Schroeder A, et al.
Nat Nanotechnol . 2020 Apr; 15(6):500-506. PMID: 32313220
Capturing the dynamics of live cell populations with nanoscale resolution poses a significant challenge, primarily owing to the speed-resolution trade-off of existing microscopy techniques. Flow cytometry would offer sufficient throughput,...
9.
Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, et al.
ACS Nano . 2019 Sep; 13(10):11008-11021. PMID: 31503443
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC) limits drug penetration into the tumor and is associated with poor prognosis. Here, we demonstrate that a pretreatment based on a...
10.
da Silva D, Kaduri M, Poley M, Adir O, Krinsky N, Shainsky-Roitman J, et al.
Chem Eng J . 2019 Aug; 340:9-14. PMID: 31384170
Polylactic acid (PLA) is the most commonly used biodegradable polymer in clinical applications today. Examples range from drug delivery systems, tissue engineering, temporary and long-term implantable devices; constantly expanding to...