Nitzan Krinsky
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Explore the profile of Nitzan Krinsky including associated specialties, affiliations and a list of published articles.
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14
Citations
557
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Recent Articles
1.
Krinsky N, Sizikov S, Nissim S, Dror A, Sas A, Prinz H, et al.
J Thromb Haemost
. 2023 Apr;
21(9):2569-2584.
PMID: 37054916
Background: COVID-19 severity and its late complications continue to be poorly understood. Neutrophil extracellular traps (NETs) form in acute COVID-19, likely contributing to morbidity and mortality. Objectives: This study evaluated...
2.
Chen G, Levin R, Landau S, Kaduri M, Adir O, Ianovici I, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(38):e2207525119.
PMID: 36095208
Progress in bottom-up synthetic biology has stimulated the development of synthetic cells (SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing diseased natural cells and addressing medical needs. Here, we...
3.
Adir O, Sharf-Pauker N, Chen G, Kaduri M, Krinsky N, Shainsky-Roitman J, et al.
J Vis Exp
. 2020 May;
(158).
PMID: 32391815
The bottom-up assembly approach for construction of synthetic cells is an effective tool for isolating and investigating cellular processes in a cell mimicking environment. Furthermore, the development of cell-free expression...
4.
Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, et al.
ACS Nano
. 2019 Sep;
13(10):11008-11021.
PMID: 31503443
Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC) limits drug penetration into the tumor and is associated with poor prognosis. Here, we demonstrate that a pretreatment based on a...
5.
da Silva D, Kaduri M, Poley M, Adir O, Krinsky N, Shainsky-Roitman J, et al.
Chem Eng J
. 2019 Aug;
340:9-14.
PMID: 31384170
Polylactic acid (PLA) is the most commonly used biodegradable polymer in clinical applications today. Examples range from drug delivery systems, tissue engineering, temporary and long-term implantable devices; constantly expanding to...
6.
Adir O, Poley M, Chen G, Froim S, Krinsky N, Shklover J, et al.
Adv Mater
. 2019 Jul;
32(13):e1901989.
PMID: 31286573
Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing the goal of precision medicine-tailoring the best treatment for each cancer patient. Recent conversion between these two...
7.
Abumanhal-Masarweh H, da Silva D, Poley M, Zinger A, Goldman E, Krinsky N, et al.
J Control Release
. 2019 Jun;
307:331-341.
PMID: 31238049
Lipid nanoparticles are used widely as anticancer drug and gene delivery systems. Internalizing into the target cell is a prerequisite for the proper activity of many nanoparticulate drugs. We show...
8.
Abumanhal-Masarweh H, Koren L, Zinger A, Yaari Z, Krinsky N, Kaneti G, et al.
J Control Release
. 2019 Jan;
296:1-13.
PMID: 30615983
Acidic pH in the tumor microenvironment is associated with cancer metabolism and creates a physiological barrier that prevents from drugs to penetrate cells. Specifically, ionizable weak-base drugs, such as doxorubicin,...
9.
Krinsky N, Kaduri M, Zinger A, Shainsky-Roitman J, Goldfeder M, Benhar I, et al.
Adv Healthc Mater
. 2017 Dec;
7(9):e1701163.
PMID: 29283226
Synthetic cells, artificial cell-like particles, capable of autonomously synthesizing RNA and proteins based on a DNA template, are emerging platforms for studying cellular functions and for revealing the origins-of-life. Here,...
10.
Krinsky N, Kaduri M, Shainsky-Roitman J, Goldfeder M, Ivanir E, Benhar I, et al.
PLoS One
. 2016 Oct;
11(10):e0165137.
PMID: 27768741
Cell-free protein synthesis (CFPS) systems are important laboratory tools that are used for various synthetic biology applications. Here, we present a simple and inexpensive laboratory-scale method for preparing a CFPS...