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Omar A Ramirez

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Articles 11
Citations 229
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1.
Gleitze S, Ramirez O, Vega-Vasquez I, Stefan E, Bengtson C, Paula-Lima A, et al.
Biochem Biophys Res Commun . 2025 Mar; 754:151445. PMID: 40022811
The brain constantly adapts to environmental changes by modifying the expression of genes that enable synaptic plasticity, learning and memory. The expression of several of these genes requires nuclear calcium...
2.
Ramirez O, Hellwig A, Zhang Z, Bading H
Cells . 2025 Feb; 14(3). PMID: 39936986
Focal swellings of dendrites ("dendritic blebbing") together with structural damage of mitochondria and the endoplasmic reticulum (ER) are morphological hallmarks of glutamate neurotoxicity, also known as excitotoxicity. These pathological alterations...
3.
Gleitze S, Ramirez O, Vega-Vasquez I, Yan J, Lobos P, Bading H, et al.
Antioxidants (Basel) . 2023 Mar; 12(3). PMID: 36978954
Ferroptosis, a newly described form of regulated cell death, is characterized by the iron-dependent accumulation of lipid peroxides, glutathione depletion, mitochondrial alterations, and enhanced lipoxygenase activity. Inhibition of glutathione peroxidase...
4.
Lobos P, Cordova A, Vega-Vasquez I, Ramirez O, Adasme T, Toledo J, et al.
Proc Natl Acad Sci U S A . 2021 Aug; 118(33). PMID: 34389673
The expression of several hippocampal genes implicated in learning and memory processes requires that Ca signals generated in dendritic spines, dendrites, or the soma in response to neuronal stimulation reach...
5.
Ramirez O, Cordova A, Cerda M, Lobos P, Hartel S, Couve A, et al.
Cell Calcium . 2021 Apr; 96:102399. PMID: 33812310
Neuronal Ca signals are fundamental for synaptic transmission and activity-dependent changes in gene expression. Voltage-gated Ca channels and N-methyl-d-aspartate receptors play major roles in mediating external Ca entry during action...
6.
Valenzuela J, Jaureguiberry-Bravo M, Salas D, Ramirez O, Cornejo V, Lu H, et al.
J Cell Sci . 2014 Jun; 127(Pt 15):3382-95. PMID: 24895402
In neurons, secretory organelles within the cell body are complemented by the dendritic endoplasmic reticulum (ER) and Golgi outposts (GOPs), whose role in neurotransmitter receptor trafficking is poorly understood. γ-aminobutyric...
7.
Macias A, Trujillo G, Dubey L, Ramirez O, Arreguin V, Munoz J, et al.
Rev Invest Clin . 2014 Apr; 65(5):399-402. PMID: 24687339
Background: The detection of asymptomatic bacteriuria in preadolescent girls may be important due to its effects on subsequent pregnancies. Objective: To describe the prevalence of asymptomatic bacteriuria in preadolescent girls...
8.
Vidal R, Fuentes P, Valenzuela J, Alvarado-Diaz C, Ramirez O, Kukuljan M, et al.
Mol Cell Neurosci . 2012 Jul; 51(1-2):1-11. PMID: 22828129
The formation of the nervous systems requires processes that coordinate proliferation, differentiation and migration of neuronal cells, which extend axons, generate dendritic branching and establish synaptic connections during development. The...
9.
Ramirez O, Hartel S, Couve A
Biol Res . 2011 Jul; 44(1):17-23. PMID: 21720677
Neurons are highly polarized, but the trafficking mechanisms that operate in these cells and the topological organization of their secretory organelles are still poorly understood. Particularly incipient is our knowledge...
10.
Ramirez O, Couve A
Trends Cell Biol . 2011 Jan; 21(4):219-27. PMID: 21215635
Neurons are highly polarized cells whose dendrites and axons extend long distances from the cell body to form synapses that mediate neuronal communication. The trafficking of membrane lipids and proteins...