Om Basukala
Overview
Explore the profile of Om Basukala including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
10
Citations
150
Followers
0
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Recent Articles
1.
Trejo-Cerro O, Basukala O, Myers M, Banks L
Tumour Virus Res
. 2024 Mar;
17:200279.
PMID: 38485055
Multiple cellular pathways are affected by HPV E6 and E7 oncoproteins, including endocytic and cellular trafficking. HPV-16 E7 can target the adaptor protein (AP) complex, which contains proteins important during...
2.
Basukala O, Trejo-Cerro O, Myers M, Pim D, Massimi P, Thomas M, et al.
mBio
. 2022 Oct;
13(6):e0230222.
PMID: 36255238
Human papillomavirus (HPV) E7 plays a major role in HPV-induced malignancy, perturbing cell cycle regulation, and driving cell proliferation. Major targets of cancer-causing HPV E7 proteins are the pRB family...
3.
Dizanzo M, Bugnon Valdano M, Basukala O, Banks L, Gardiol D
BMC Cancer
. 2022 Sep;
22(1):1015.
PMID: 36153517
Background: Oncogenic Human Papillomaviruses (HPVs) base their transforming potential on the action of both E6 and E7 viral oncoproteins, which perform cooperative or antagonistic actions and thus interfere with a...
4.
Ramon A, Basukala O, Massimi P, Thomas M, Perera Y, Banks L, et al.
Viruses
. 2022 Aug;
14(8).
PMID: 36016303
CIGB-300 is a clinical-grade anti-Protein Kinase CK2 peptide, binding both its substrate's phospho-acceptor site and the CK2α catalytic subunit. The cyclic p15 inhibitory domain of CIGB-300 was initially selected in...
5.
Basukala O, Banks L
Viruses
. 2021 Oct;
13(10).
PMID: 34696321
Infection with HPV starts with the access of the viral particles to basal cells in the epidermis, potentially via microtraumas to the skin. The basal cells are able to keep...
6.
Basukala O, Sarabia-Vega V, Banks L
Biol Chem
. 2020 Jan;
401(5):585-599.
PMID: 31913845
Human papillomaviruses (HPVs) are major human carcinogens, causing around 5% of all human cancers, with cervical cancer being the most important. These tumors are all driven by the two HPV...
7.
Basukala O, Mittal S, Massimi P, Bestagno M, Banks L
PLoS Pathog
. 2019 May;
15(5):e1007769.
PMID: 31116803
The Human Papillomavirus E7 oncoprotein plays an essential role in the development and maintenance of malignancy, which it achieves through targeting a number of critical cell control pathways. An important...
8.
Szalmas A, Tomaic V, Basukala O, Massimi P, Mittal S, Konya J, et al.
J Virol
. 2017 Jan;
91(7).
PMID: 28100625
Activation of signaling pathways ensuring cell growth is essential for the proliferative competence of human papillomavirus (HPV)-infected cells. Tyrosine kinases and phosphatases are key regulators of cellular growth control pathways....
9.
Mishra S, Basukala P, Basukala O, Parajuli K, Pokhrel B, Rijal B
Curr Microbiol
. 2014 Sep;
70(1):128-34.
PMID: 25239012
Microbial biofilms pose great threat for patients requiring indwelling medical devices (IMDs) as it is difficult to remove them. It is, therefore, crucial to follow an appropriate method for the...
10.
Manandhar K, Yadav T, Prajapati V, Basukala O, Aganja R, Dude A, et al.
Adv Exp Med Biol
. 2014 Mar;
808:77-91.
PMID: 24595612
With widespread resistance to pentavalent antimonial in the endemic eastern terai belt of Nepal and Bihar, India, Amphotericin B deoxycholate is now the first-line antileishmanial drug for the treatment of...