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Olivier T Guenat

Explore the profile of Olivier T Guenat including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 620
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Recent Articles
1.
Rodrigues Sousa E, de Brot S, Zoni E, Zeinali S, Brunello A, Scarpa M, et al.
Oncogene . 2024 Nov; 44(7):462-475. PMID: 39592836
CRIPTO (or CR-1 or TDGF1) is a protein that plays an active role in tumor initiation and progression. We have confirmed that increased expression of CRIPTO is associated with clinical...
2.
Schmid K, Zeinali S, Moser S, Dubey C, Schneider S, Deng H, et al.
Front Bioeng Biotechnol . 2024 Oct; 12:1457884. PMID: 39439549
Metastatic lung cancer remains a leading cause of death worldwide, with its intricate metastatic cascade posing significant challenges to researchers and clinicians. Despite substantial progress in understanding this cascade, many...
3.
Nizamoglu M, Joglekar M, Almeida C, Callerfelt A, Dupin I, Guenat O, et al.
Eur Respir Rev . 2023 Jul; 32(169). PMID: 37495250
Chronic lung diseases result from alteration and/or destruction of lung tissue, inevitably causing decreased breathing capacity and quality of life for patients. While animal models have paved the way for...
4.
van Os L, Engelhardt B, Guenat O
Front Bioeng Biotechnol . 2023 Jun; 11:1191104. PMID: 37324438
Viral and bacterial infections continue to pose significant challenges for numerous individuals globally. To develop novel therapies to combat infections, more insight into the actions of the human innate and...
5.
van Os L, Yeoh J, Witz G, Ferrari D, Krebs P, Chandorkar Y, et al.
Eur J Pharm Sci . 2023 Jun; 187:106485. PMID: 37270149
Acute respiratory distress syndrome (ARDS) is a severe lung condition with high mortality and various causes, including lung infection. No specific treatment is currently available and more research aimed at...
6.
Zamprogno P, Schulte J, Ferrari D, Rechberger K, Sengupta A, van Os L, et al.
Adv Exp Med Biol . 2023 May; 1413:191-211. PMID: 37195532
Since the publication of the first lung-on-a-chip in 2010, research has made tremendous progress in mimicking the cellular environment of healthy and diseased alveoli. As the first lung-on-a-chip products have...
7.
Sengupta A, Dorn A, Jamshidi M, Schwob M, Hassan W, De Maddalena L, et al.
Front Pharmacol . 2023 Mar; 14:1114739. PMID: 36959848
Prolonged exposure to environmental respirable toxicants can lead to the development and worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and fibrosis. The limited number...
8.
Ferrari D, Sengupta A, Heo L, Petho L, Michler J, Geiser T, et al.
iScience . 2023 Mar; 26(3):106198. PMID: 36879808
The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)). Upon alteration of...
9.
Sengupta A, Roldan N, Kiener M, Froment L, Raggi G, Imler T, et al.
Front Toxicol . 2022 Jul; 4:840606. PMID: 35832493
The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the investigation of complex disease pathomechanisms, are increasingly relying on lung models. This is due to the...
10.
Tang Y, Gao H, Kurth F, Burr L, Petropoulos K, Migliorelli D, et al.
Biosens Bioelectron . 2021 Jul; 192:113491. PMID: 34271399
The Lateral Flow Immuno Assay (LFIA) is a well-established technique that provides immediate results without high-cost laboratory equipment and technical skills from the users. However, conventional colorimetric LFIA strips suffer...