Olivier Mignen
Overview
Explore the profile of Olivier Mignen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
55
Citations
1043
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Proteau S, Krossa I, Husser C, Gueguinou M, Sella F, Bille K, et al.
EMBO Mol Med
. 2024 Aug;
16(9):2262-2267.
PMID: 39164473
No abstract available.
2.
Karoui S, Dhiabi M, Fakhfakh M, Abid S, Limanton E, Le Guevel R, et al.
Pharmaceuticals (Basel)
. 2024 Apr;
17(4).
PMID: 38675418
The synthesis of a series of new -benzylidene derivatives of 3-amino-4-imino-3,5-dihydro-4-chromeno[2,3-]pyrimidine bearing two points of molecular diversity is reported. These new compounds were synthesized in five steps including two steps...
3.
Scaviner J, Bagacean C, Christian B, Renaudineau Y, Mignen O, Abdoul-Azize S
Eur J Pharmacol
. 2024 Mar;
971:176515.
PMID: 38547958
Orai1 channel capacity to control store-operated Ca entry (SOCE) and B-cell functions is poorly understood and more specifically in B-cell cancers, including human lymphoma and leukemia. As compared to normal...
4.
Mignen O, Vannier J, Schneider P, Renaudineau Y, Abdoul-Azize S
Biochem Pharmacol
. 2023 Dec;
219:115955.
PMID: 38040093
In non-excitable cells, Orai proteins represent the main channel for Store-Operated Calcium Entry (SOCE), and also mediate various store-independent Calcium Entry (SICE) pathways. Deregulation of these pathways contribute to increased...
5.
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Proteau S, Krossa I, Husser C, Gueguinou M, Sella F, Bille K, et al.
EMBO Mol Med
. 2023 Nov;
15(12):e17719.
PMID: 37966164
Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome-wide CRISPR-Cas9 knockout screen, which revealed the LKB1-SIK2 module in restraining uveal...
6.
Kouba S, Buscaglia P, Gueguinou M, Ibrahim S, Felix R, Guibon R, et al.
Cell Calcium
. 2023 Aug;
115:102794.
PMID: 37597301
Prostate cancer (PCa) represents one of the most frequent diagnosed cancer in males worldwide. Due to routine screening tests and the efficiency of available treatments, PCa-related deaths have significantly decreased...
7.
New insights into the regulation of , an enzyme involved in intellectual deficiency in Down syndrome
Conan P, Leon A, Caroff N, Rollet C, Chair L, Martin J, et al.
Front Neurosci
. 2023 Jan;
16:1110163.
PMID: 36711154
Down syndrome (DS), the most frequent chromosomic aberration, results from the presence of an extra copy of chromosome 21. The identification of genes which overexpression contributes to intellectual disability (ID)...
8.
Conan P, Leon A, Gourdel M, Rollet C, Chair L, Caroff N, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743210
CBS encodes a pyridoxal 5'-phosphate-dependent enzyme that catalyses the condensation of homocysteine and serine to form cystathionine. Due to its implication in some cancers and in the cognitive pathophysiology of...
9.
Michee-Cospolite M, Boudigou M, Grasseau A, Simon Q, Mignen O, Pers J, et al.
Front Immunol
. 2022 Apr;
13:818814.
PMID: 35359922
Regulatory B cells (Bregs) have been highlighted in very different pathology settings including autoimmune diseases, allergy, graft rejection, and cancer. Improving tools for the characterization of Bregs has become the...
10.
Pierre O, Fouchard M, Le Goux N, Buscaglia P, Leschiera R, Lewis R, et al.
Mar Drugs
. 2021 Aug;
19(7).
PMID: 34356812
Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins. Both toxins cause sensory symptoms such as paresthesia, cold...