Olivier Delezay
Overview
Explore the profile of Olivier Delezay including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
294
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0
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Recent Articles
1.
Mismetti V, Delavenne X, Montani D, Bezzeghoud S, Delezay O, Hodin S, et al.
Respir Res
. 2023 Nov;
24(1):273.
PMID: 37936223
Background: Interstitial lung disease (ILD) and pulmonary hypertension (PH) represent the major causes of mortality in systemic sclerosis (SSc). Patients with systemic sclerosis and combined PH and ILD (SSc-PH-ILD) generally...
2.
El-Battari A, Rodriguez L, Chahinian H, Delezay O, Fantini J, Yahi N, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34768981
We present here a gene therapy approach aimed at preventing the formation of Ca-permeable amyloid pore oligomers that are considered as the most neurotoxic structures in both Alzheimer's and Parkinson's...
3.
Delezay O, Hodin S, He Z, Ollier E, Delavenne X
Toxicol Appl Pharmacol
. 2021 Aug;
429:115683.
PMID: 34411582
Unfractionated heparin (UFH) is a widely used anticoagulant that possess numerous properties including anti-inflammatory, anti-viral, anti-angiogenesis, and anti-metastatic effects. The effect of this drug was evaluated on the podocyte, an...
4.
Saib S, Hodin S, He Z, Delezay O, Delavenne X
Fundam Clin Pharmacol
. 2020 Nov;
35(4):732-743.
PMID: 33185296
Active tubular secretion plays a major role in renal excretion of drugs thanks to the presence of many membrane transporters such as ABC transporters. These proteins facilitate drug transfer into...
5.
Effects of heparin and derivatives on podocytes: An in vitro functional and morphological evaluation
Delezay O, He Z, Sabido O, Hodin S, Bin V, Saleem M, et al.
J Cell Physiol
. 2019 Jan;
234(9):15438-15449.
PMID: 30684278
Unfractionated heparin (UFH) and low molecular heparin derivatives (LMWH) display numerous biological properties in addition to their anticoagulant effects. However, due to the physicochemical heterogeneity of these drugs, a better...
6.
Margelidon-Cozzolino V, Hodin S, Jacqueroux E, Delezay O, Bertoletti L, Delavenne X
J Pharmacol Exp Ther
. 2018 Mar;
365(3):519-525.
PMID: 29572341
Because of their lower bleeding risk and simplicity of use, direct oral anticoagulants (DOACs) could represent an interesting alternative to conventional anticoagulant treatment with vitamin K antagonists for patients with...
7.
Delezay O, He Z, Hodin S, Saleem M, Mismetti P, Perek N, et al.
Exp Cell Res
. 2017 Nov;
361(2):300-307.
PMID: 29107066
The kidney is an organ that plays a major role in the excretion of numerous compounds such as drugs and chemicals. However, a great number of pharmacological molecules are nephrotoxic,...
8.
Hodin S, Basset T, Jacqueroux E, Delezay O, Clotagatide A, Perek N, et al.
Eur J Drug Metab Pharmacokinet
. 2017 Sep;
43(2):183-191.
PMID: 28895074
Background: Pharmacokinetics of direct oral anticoagulants (DOACs) are influenced by ATP-binding cassette (ABC) transporters such as P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). Objectives: To better understand the role...
9.
Gagneux-Brunon A, Nasri D, Terrasse R, Saune K, Gagnieu M, Fresard A, et al.
Curr HIV Res
. 2015 Nov;
14(4):316-23.
PMID: 26577801
Background: The semen of HIV-1 infected men represents the main vector of HIV-1 spread following sexual transmission of cell-free or cell-associated virions. Objective: The present study aimed to assess the...
10.
SDe aint Jean A, Bourlet T, Delezay O
Curr HIV Res
. 2015 Jun;
13(6):479-89.
PMID: 26105156
AIDS remains one of the world's most serious health challenges, with 35 million people living with HIV worldwide at the end of 2013. HIV sexual transmission accounts for the overwhelming...