Olivia Sirpilla
Overview
Explore the profile of Olivia Sirpilla including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
129
Followers
0
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Recent Articles
1.
Sirpilla O, Kenderian S
Immunotherapy
. 2024 Sep;
16(14-15):907-911.
PMID: 39268677
No abstract available.
2.
Stewart C, Siegler E, Sakemura R, Cox M, Huynh T, Kimball B, et al.
Nat Commun
. 2024 Sep;
15(1):7921.
PMID: 39266501
Durable response to chimeric antigen receptor T (CART) cell therapy remains limited in part due to CART cell exhaustion. Here, we investigate the regulation of CART cell exhaustion with three...
3.
Sirpilla O, Sakemura R, Hefazi M, Huynh T, Can I, Girsch J, et al.
Nat Biomed Eng
. 2024 Apr;
8(4):443-460.
PMID: 38561490
Allogeneic mesenchymal stromal cells (MSCs) are a safe treatment option for many disorders of the immune system. However, clinical trials using MSCs have shown inconsistent therapeutic efficacy, mostly owing to...
4.
Underwood A, Rasicci D, Hinds D, Mitchell J, Zieba J, Mills J, et al.
Genes (Basel)
. 2023 Jan;
14(1).
PMID: 36672963
The SOX transcription factor family is pivotal in controlling aspects of development. To identify genotype-phenotype relationships of SOX proteins, we performed a non-biased study of SOX using 1890 open-reading frame...
5.
Kankeu Fonkoua L, Sirpilla O, Sakemura R, Siegler E, Kenderian S
Mol Ther Oncolytics
. 2022 Apr;
25:69-77.
PMID: 35434273
Chimeric antigen receptor (CAR) T cell therapy has demonstrated remarkable outcomes in individuals with hematological malignancies, but its success has been hindered by barriers intrinsic to the tumor microenvironment (TME),...
6.
Sirpilla O, Bauss J, Gupta R, Underwood A, Qutob D, Freeland T, et al.
J Proteome Res
. 2020 Jul;
19(11):4275-4290.
PMID: 32686937
SARS-CoV-2 (COVID-19) has infected millions of people worldwide, with lethality in hundreds of thousands. The rapid publication of information, both regarding the clinical course and the viral biology, has yielded...
7.
Gupta R, Charron J, Stenger C, Painter J, Steward H, Cook T, et al.
J Biol Chem
. 2020 Jun;
295(33):11742-11753.
PMID: 32587094
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged the speed at which laboratories can discover the viral composition and study health outcomes. The small ∼30-kb...
8.
Gupta R, Charron J, Stenger C, Painter J, Steward H, Cook T, et al.
bioRxiv
. 2020 Jun;
PMID: 32511397
The SARS-CoV-2 pandemic, starting in 2019, has challenged the speed at which labs perform science, ranging from discoveries of the viral composition to handling health outcomes in humans. The small...
9.
Prokop J, Shankar R, Gupta R, Leimanis M, Nedveck D, Uhl K, et al.
Physiol Genomics
. 2020 May;
52(6):255-268.
PMID: 32437232
Precision medicine requires the translation of basic biological understanding to medical insights, mainly applied to characterization of each unique patient. In many clinical settings, this requires tools that can be...