Olga Sokol
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Explore the profile of Olga Sokol including associated specialties, affiliations and a list of published articles.
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10
Citations
59
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Recent Articles
1.
Bertho A, Graeff C, Ortiz R, Giorgi M, Schuy C, Juchaux M, et al.
Sci Rep
. 2025 Mar;
15(1):7305.
PMID: 40025099
Despite remarkable advances, radiation therapy (RT) remains inefficient for some bulky tumors, radioresistant tumors, and certain pediatric tumors. Minibeam radiation therapy (MBRT) has emerged as a promising approach, reducing normal...
2.
Tinganelli W, Puspitasari-Kokko A, Sokol O, Helm A, Simoniello P, Schuy C, et al.
Int J Radiat Oncol Biol Phys
. 2024 Nov;
121(5):1282-1292.
PMID: 39608612
Purpose: In recent years, ultra-high dose rate (UHDR) irradiation has emerged as a promising innovative approach to cancer treatment. Characteristic feature of this regimen, commonly referred to as FLASH effect,...
3.
Ahmad R, Barcellini A, Baumann K, Benje M, Bender T, Bragado P, et al.
Int J Part Ther
. 2024 Sep;
13:100626.
PMID: 39258166
Particle therapy (PT) represents a significant advancement in cancer treatment, precisely targeting tumor cells while sparing surrounding healthy tissues thanks to the unique depth-dose profiles of the charged particles. Furthermore,...
4.
Sokol O, Durante M
Cancers (Basel)
. 2023 Sep;
15(18).
PMID: 37760464
Hypoxia, which is associated with abnormal vessel growth, is a characteristic feature of many solid tumors that increases their metastatic potential and resistance to radiotherapy. Carbon-ion radiation therapy, either alone...
5.
Sokol O, Cella L, Boscolo D, Horst F, Oliviero C, Pacelli R, et al.
Sci Rep
. 2022 Dec;
12(1):21792.
PMID: 36526710
Sharp dose gradients and high biological effectiveness make ions such as C an ideal tool to treat deep-seated tumors, however, at the same time, sensitive to errors in the range...
6.
Boscolo D, Kostyleva D, Schuy C, Weber U, Haettner E, Purushothaman S, et al.
Nucl Instrum Methods Phys Res A
. 2022 Nov;
1043:167464.
PMID: 36345417
Owing to the favorable depth-dose distribution and the radiobiological properties of heavy ion radiation, ion beam therapy shows an improved success/toxicity ratio compared to conventional radiotherapy. The sharp dose gradients...
7.
Kartini D, Sokol O, Talabnin C, Kobdaj C, Durante M, Kramer M, et al.
Int J Radiat Biol
. 2022 Aug;
99(3):488-498.
PMID: 35939100
Purpose: In this study, we performed biological verification measurements of cell survival of a C ion irradiation plan employing a high-resolution 3D culture setup. This allowed, in particular, to access...
8.
Tinganelli W, Sokol O, Quartieri M, Puspitasari A, Dokic I, Abdollahi A, et al.
Int J Radiat Oncol Biol Phys
. 2021 Nov;
112(4):1012-1022.
PMID: 34813912
Purpose: To establish a beam monitoring and dosimetry system to enable the FLASH dose rate carbon ion irradiation and investigate, at different oxygen concentrations, the in vitro biological response in...
9.
Hahn C, Oden J, Dasu A, Vestergaard A, Jensen M, Sokol O, et al.
Acta Oncol
. 2021 Oct;
61(2):206-214.
PMID: 34686122
Background: Clinical data suggest that the relative biological effectiveness (RBE) in proton therapy (PT) varies with linear energy transfer (LET). However, LET calculations are neither standardized nor available in clinical...
10.
Boscolo D, Kostyleva D, Javad Safari M, Anagnostatou V, Aysto J, Bagchi S, et al.
Front Oncol
. 2021 Sep;
11:737050.
PMID: 34504803
Several techniques are under development for image-guidance in particle therapy. Positron (β) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation...