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Christian Graeff

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Articles 49
Citations 574
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Recent Articles
1.
Reidel C, Pierobon E, Horst F, Gesson L, Paz A, Graeff C, et al.
Front Oncol . 2025 Mar; 15:1502960. PMID: 40078180
Tumor motion is a major challenge for scanned ion-beam therapy. In the case of lung tumors, strong under- and overdosage can be induced due to the high density gradients between...
2.
Bertho A, Graeff C, Ortiz R, Giorgi M, Schuy C, Juchaux M, et al.
Sci Rep . 2025 Mar; 15(1):7305. PMID: 40025099
Despite remarkable advances, radiation therapy (RT) remains inefficient for some bulky tumors, radioresistant tumors, and certain pediatric tumors. Minibeam radiation therapy (MBRT) has emerged as a promising approach, reducing normal...
3.
Steinsberger T, Nakas A, Vai A, Molinelli S, Donetti M, Pullia M, et al.
Phys Med Biol . 2025 Feb; 70(6). PMID: 39978068
To identify suitable combination strategies for treatment planning and beam delivery in scanned carbon ion therapy of moving tumors.. Carbon ion treatment plans for five abdominal tumors were optimized on...
4.
Simard M, Fullarton R, Volz L, Schuy C, Robertson D, Toltz A, et al.
Med Phys . 2025 Feb; PMID: 39904601
Background: Incorporating image guidance into ion beam therapy is critical for minimizing beam range uncertainties and realizing the modality's potential. One promising avenue for image guidance is to capture transmission...
5.
Fullarton R, Simard M, Volz L, Toltz A, Chung S, Schuy C, et al.
Med Phys . 2024 Nov; 52(2):1146-1158. PMID: 39530503
Background: Motion of lung tumors during radiotherapy leads to decreased accuracy of the delivered dose distribution. This is especially true for proton radiotherapy due to the finite range of the...
6.
Volz L, Korte J, Martire M, Zhang Y, Hardcastle N, Durante M, et al.
Phys Med Biol . 2024 Aug; 69(18). PMID: 39159668
Upright positioning has seen a surge in interest as a means to reduce radiotherapy (RT) cost, improve patient comfort, and, in selected cases, benefit treatment quality. In particle therapy (PT)...
7.
Mein S, Wuyckens S, Li X, Both S, Carabe A, Vera M, et al.
Radiother Oncol . 2024 Jul; 199:110434. PMID: 39009306
There is a rising interest in developing and utilizing arc delivery techniques with charged particle beams, e.g., proton, carbon or other ions, for clinical implementation. In this work, perspectives from...
8.
Volz L, Graeff C, Durante M, Collins-Fekete C
Phys Med Biol . 2023 Dec; 69(2). PMID: 38056016
We demonstrate a novel focus stacking technique to improve spatial resolution of single-event particle radiography (pRad), and exploit its potential for 3D feature detection.Focus stacking, used typically in optical photography...
9.
Sheng Y, Volz L, Wang W, Durante M, Graeff C
Z Med Phys . 2023 Jul; PMID: 37455229
Purpose: To investigate the accuracy of the treatment planning system (TPS) TRiP4D in reproducing doses computed by the clinically used TPS SyngoRT. Methods: Proton and carbon ion beam models in...
10.
Graeff C, Volz L, Durante M
Prog Part Nucl Phys . 2023 May; 131:104046. PMID: 37207092
Cancer therapy with accelerated charged particles is one of the most valuable biomedical applications of nuclear physics. The technology has vastly evolved in the past 50 years, the number of...