Olga Breitkreuz-Korff
Overview
Explore the profile of Olga Breitkreuz-Korff including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
159
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0
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Recent Articles
1.
Breitkreuz-Korff O, Tscheik C, Del Vecchio G, Dithmer S, Walther W, Orthmann A, et al.
J Control Release
. 2021 Aug;
338:137-148.
PMID: 34384796
Drug delivery to the brain is limited for most pharmaceuticals by the blood-brain barrier (BBB) where claudin-5 dominates the paraendothelial tightening. For circumventing the BBB, we identified the compound M01...
2.
Winkler L, Blasig R, Breitkreuz-Korff O, Berndt P, Dithmer S, Helms H, et al.
J Cereb Blood Flow Metab
. 2020 Feb;
41(1):132-145.
PMID: 32054373
The outcome of stroke is greatly influenced by the state of the blood-brain barrier (BBB). The BBB endothelium is sealed paracellularly by tight junction (TJ) proteins, i.e., claudins (Cldns) and...
3.
Berndt P, Winkler L, Cording J, Breitkreuz-Korff O, Rex A, Dithmer S, et al.
Cell Mol Life Sci
. 2019 Feb;
76(10):1987-2002.
PMID: 30734065
At the blood-brain barrier (BBB), claudin (Cldn)-5 is thought to be the dominant tight junction (TJ) protein, with minor contributions from Cldn3 and -12, and occludin. However, the BBB appears...
4.
Milz F, Harder A, Neuhaus P, Breitkreuz-Korff O, Walhorn V, Lubke T, et al.
Biochim Biophys Acta
. 2013 Jul;
1830(11):5287-98.
PMID: 23891937
Background: Sulf1 is a cell-surface sulfatase removing internal 6-O-sulfate groups from heparan sulfate (HS) chains. Thereby it modulates the activity of HS-dependent growth factors. For HS interaction Sulf1 employs a...