Author: Oleg Eltsov | MedLuna.com

1.

Nitrothiadiazolo[3,2-a]pyrimidines as promising antiglycating agents

Savateev K, Fedotov V, Butorin I, Eltsov O, Slepukhin P, Ulomsky E, et al.

Eur J Med Chem . 2019 Nov; 185:111808. PMID: 31683103

Managing the advanced glycation end-products (AGEs) concentration is a reliable approach to achieve control over the pathogenesis of diabetic vascular complications. Inhibition of dipeptidyl peptidase-4 (DPP-4) is also an attractive...

2.

Identification and analytical characterization of the synthetic cathinone N-butylhexedrone

Shevyrin V, Eltsov O, Shafran Y

Drug Test Anal . 2019 Nov; 12(1):159-163. PMID: 31667946

No abstract available.

3.

Mass spectrometric properties of N-(2-methoxybenzyl)-2-(2,4,6-trimethoxyphenyl)ethanamine (2,4,6-TMPEA-NBOMe), a new representative of designer drugs of NBOMe series and derivatives thereof

Shevyrin V, Kupriyanova O, Lebedev A, Melkozerov V, Eltsov O, Shafran Y, et al.

J Mass Spectrom . 2016 Jul; 51(10):969-979. PMID: 27388323

Emergence of new psychoactive substances, hallucinogenic phenethylamines in particular, in illicit market is a serious threat to human health in global scale. We have detected and identified N-(2-methoxybenzyl)-2-(2,4,6-trimethoxyphenyl)ethanamine (2,4,6-TMPEA-NBOMe), a...

4.

Synthetic cannabinoid 3-benzyl-5-[1-(2-pyrrolidin-1-ylethyl)-1H-indol-3-yl]-1,2,4-oxadiazole. The first detection in illicit market of new psychoactive substances

Shevyrin V, Melkozerov V, Eltsov O, Shafran Y, Morzherin Y

Forensic Sci Int . 2016 Jan; 259:95-100. PMID: 26771874

We were the first to detect 3-benzyl-5-[1-(2-pyrrolidin-1-ylethyl)-1H-indol-3-yl]-1,2,4-oxadiazole (given name BzODZ-EPyr) as a new synthetic cannabinoid, in illegal market of new psychoactive compounds (NPS). The compound was known only from pharmaceutical...

5.

Identification and analytical characteristics of synthetic cannabinoids with an indazole-3-carboxamide structure bearing a N-1-methoxycarbonylalkyl group

Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Shafran Y, Morzherin Y, et al.

Anal Bioanal Chem . 2015 Apr; 407(21):6301-15. PMID: 25893797

Illicit new psychoactive substances (NPS) are a serious threat to health throughout the world. Such NPS do not usually pass preliminary pharmacological trials. In 2014, we identified a series of...

6.

Synthetic cannabinoids as designer drugs: new representatives of indol-3-carboxylates series and indazole-3-carboxylates as novel group of cannabinoids. Identification and analytical data

Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Baranovsky A, Shafran Y

Forensic Sci Int . 2014 Oct; 244:263-75. PMID: 25305529

By means of gas chromatography with mass spectrometry detection (GC-MS), including high resolution mass spectrometry (GC-HRMS) together with ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry...

7.

3-Naphthoylindazoles and 2-naphthoylbenzoimidazoles as novel chemical groups of synthetic cannabinoids: chemical structure elucidation, analytical characteristics and identification of the first representatives in smoke mixtures

Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Morzherin Y, Shafran Y

Forensic Sci Int . 2014 Jul; 242:72-80. PMID: 25036783

By means of gas chromatography with mass spectrometry detection (GC-MS), including high resolution mass spectrometry (GC-HRMS) together with ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry...

8.

Analytical characterization of some synthetic cannabinoids, derivatives of indole-3-carboxylic acid

Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Shafran Y

Forensic Sci Int . 2013 Sep; 232(1-3):1-10. PMID: 24053858

By means of gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and...

9.

Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety

Shevyrin V, Melkozerov V, Nevero A, Eltsov O, Morzherin Y, Shafran Y

Forensic Sci Int . 2013 Jan; 226(1-3):62-73. PMID: 23280248

By means of gas chromatography with mass spectrometry detector (GC-MS), liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance spectroscopy (NMR), structure of a series from a novel class of synthetic...

10.

Self condensation of enamines mediated by acetylation. A novel approach to 1-(azol-5-yl)-(1E,3Z)-butadiene-4-N,N-dimethylamines

Shafran Y, Rozin Y, Beryozkina T, Zhidovinov S, Eltsov O, Subbotina J, et al.

Org Biomol Chem . 2012 Apr; 10(30):5795-8. PMID: 22508270

Novel self-condensation of 3-(azol-5-yl)-1,1-dimethylenamines has been found to form new C-C bonds leading to 2,4-(1,2,3-triazole-1,2,3-thiadiazole-3-phenylisothiazole)-(1E,3Z)-5-yl-butadiene-1-amines. The discovered reaction represents a new example of C-H functionalization in unsaturated systems and can...