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Olda A Lapchinskaya

Explore the profile of Olda A Lapchinskaya including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 22
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Recent Articles
1.
Alferova V, Baranova A, Belozerova O, Gulyak E, Mikhaylov A, Solovev Y, et al.
Antibiotics (Basel) . 2025 Jan; 13(12. PMID: 39766557
Irumamycin (Iru) is a complex polyketide with pronounced antifungal activity produced by a type I polyketide (PKS) synthase. Iru features a unique hemiketal ring and an epoxide group, making its...
2.
Kravchenko T, Paramonov A, Kudzhaev A, Efimova S, Khorev A, Kudryakova G, et al.
J Nat Prod . 2024 Feb; 87(4):664-674. PMID: 38362867
We report the molecular mechanism of action of gausemycins and the isolation of new members of the family, gausemycins C (), D (), E (), and F (), the minor...
3.
Poshvina D, Dilbaryan D, Kasyanov S, Sadykova V, Lapchinskaya O, Rogozhin E, et al.
Front Microbiol . 2022 Oct; 13:963979. PMID: 36246291
Gausemycin A is the first member of the novel lipoglycopeptides family produced by INA-Ac-5812. Gausemycin A has a pronounced bactericidal activity against methicillin-resistant . However, the ability of to be...
4.
Tyurin A, Alferova V, Paramonov A, Shuvalov M, Kudryakova G, Rogozhin E, et al.
Angew Chem Int Ed Engl . 2021 May; 60(34):18694-18703. PMID: 34009717
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA-Ac-5812. Two major components of the mixture, named gausemycins A and B, were isolated, and their structures were...
5.
Vasilchenko A, Julian W, Lapchinskaya O, Katrukha G, Sadykova V, Rogozhin E
Front Microbiol . 2020 Oct; 11:556063. PMID: 33072016
In this work, we report the isolation and detailed functional characterization for the new non-ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of INA-Ac-5812. According to its chemical structure,...