Olaf Ansorge
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Explore the profile of Olaf Ansorge including associated specialties, affiliations and a list of published articles.
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Articles
129
Citations
5476
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Recent Articles
1.
Mawhinney G, Higham H, Leedham S, Ansorge O
BMC Cancer
. 2025 Mar;
25(1):420.
PMID: 40055688
Introduction: Primary tumours of the brain and spine are rare, heterogeneous, and frequently associated with significant morbidity and mortality. Advances in precision oncology and personalised medicine offer the potential to...
2.
Somogyi P, Horie S, Lukacs I, Hunter E, Sarkany B, Viney T, et al.
Eur J Neurosci
. 2025 Jan;
61(1):e16652.
PMID: 39810425
Cannabinoid receptor 1 (CB1) regulates synaptic transmission through presynaptic receptors in nerve terminals, and its physiological roles are of clinical relevance. The cellular sources and synaptic targets of CB1-expressing terminals...
3.
Vaughan D, Fumi R, Theilmann Jensen M, Hodgson M, Georgiades T, Wu L, et al.
Mov Disord
. 2024 Sep;
39(12):2285-2291.
PMID: 39301998
Background: Seed amplification assay (SAA) testing has been developed as a biomarker for the diagnosis of α-synuclein-related neurodegenerative disorders. Objective: The objective of this study was to assess the rate...
4.
Baugh R, Khalique H, Page E, Lei-Rossmann J, Wan P, Johanssen T, et al.
J Immunother Cancer
. 2024 May;
12(5).
PMID: 38724464
Background: Glioblastoma (GBM) almost invariably becomes resistant towards conventional treatment of radiotherapy and temozolomide (TMZ) chemotherapy, partly due to subpopulations of intrinsically resistant glioma stem-like cells (GSC). The oncolytic herpes...
5.
Kurtyka M, Wessely F, Bau S, Ifie E, He L, de Wit N, et al.
Eur J Cell Biol
. 2024 Mar;
103(2):151406.
PMID: 38547677
Despite extensive research, targeted delivery of substances to the brain still poses a great challenge due to the selectivity of the blood-brain barrier (BBB). Most molecules require either carrier- or...
6.
Ma R, Livermore L, Taylor L, Laycock J, Williams S, Ansorge O, et al.
World Neurosurg
. 2024 Mar;
185:e1268-e1279.
PMID: 38514030
Objectives: Using a laboratory-based optical setup, we show that 5-aminolevulinic acid (5ALA) fluorescence is better detected using the endoscope than the microscope. Furthermore, we present our case series of fully...
7.
Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith A, Willumsen N, et al.
Nat Commun
. 2024 Mar;
15(1):2243.
PMID: 38472200
Brain perfusion and blood-brain barrier (BBB) integrity are reduced early in Alzheimer's disease (AD). We performed single nucleus RNA sequencing of vascular cells isolated from AD and non-diseased control brains...
8.
Nolan M, Scott C, Hof P, Ansorge O
J Comp Neurol
. 2024 Jan;
532(1):e25567.
PMID: 38289193
Betz cells, named in honor of Volodymyr Betz (1834-1894), who described them as "giant pyramids" in the primary motor cortex of primates and other mammalian species, are layer V extratelencephalic...
9.
Zhou Z, Kim J, Huang A, Nolan M, Park J, Doan R, et al.
bioRxiv
. 2023 Dec;
PMID: 38077003
Although mutations in dozens of genes have been implicated in familial forms of amyotrophic lateral sclerosis (fALS) and frontotemporal degeneration (fFTD), most cases of these conditions are sporadic (sALS and...
10.
Davis S, Scott C, Oetjen J, Charles P, Kessler B, Ansorge O, et al.
Nat Commun
. 2023 Nov;
14(1):7710.
PMID: 38001067
The spatial organisation of cellular protein expression profiles within tissue determines cellular function and is key to understanding disease pathology. To define molecular phenotypes in the spatial context of tissue,...