Okihide Hikosaka
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Explore the profile of Okihide Hikosaka including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Chen H, Kunimatsu J, Oya T, Imaizumi Y, Hori Y, Matsumoto M, et al.
iScience
. 2025 Mar;
28(3):111936.
PMID: 40034850
Neural dynamics are thought to reflect computations that relay and transform information in the brain. Previous studies have identified the neural population dynamics in many individual brain regions as a...
2.
Periaqueductal gray passes over disappointment and signals continuity of remaining reward expectancy
Lee H, Hikosaka O
Res Sq
. 2025 Feb;
PMID: 39989963
Disappointment is a vital factor in the learning and adjustment of strategies in reward-seeking behaviors. It helps them conserve energy in environments where rewards are scarce, while also increasing their...
3.
Periaqueductal gray passes over disappointment and signals continuity of remaining reward expectancy
Lee H, Hikosaka O
bioRxiv
. 2025 Jan;
PMID: 39763985
Disappointment is a vital factor in the learning and adjustment of strategies in reward-seeking behaviors. It helps them conserve energy in environments where rewards are scarce, while also increasing their...
4.
Yoshida A, Hikosaka O
bioRxiv
. 2025 Jan;
PMID: 39763854
The basal ganglia play a crucial role in action selection by facilitating desired movements and suppressing unwanted ones. The substantia nigra pars reticulata (SNr), a key output nucleus, facilitates movement...
5.
Yoshida A, Hikosaka O
J Neurosci
. 2024 Nov;
44(49).
PMID: 39496488
Behaving as desired requires selecting the appropriate behavior and inhibiting the selection of inappropriate behavior. This inhibitory function involves multiple processes, such as reactive and proactive inhibition, instead of a...
6.
Kunimatsu J, Amita H, Hikosaka O
iScience
. 2024 Jun;
27(6):110043.
PMID: 38868184
Recent studies have suggested that the basal ganglia, the center of stimulus-reward associative learning, are involved in social behavior. However, the role of the basal ganglia in social information processing...
7.
Lee H, Kim H, Hikosaka O
Neurosci Biobehav Rev
. 2024 May;
162:105719.
PMID: 38759470
To improve the initiation and speed of intended action, one of the crucial mechanisms is suppressing unwanted movements that interfere with goal-directed behavior, which is observed relatively aberrant in Parkinson's...
8.
Yoshida A, Hikosaka O
bioRxiv
. 2024 May;
PMID: 38712157
Behaving as desired requires selecting the appropriate behavior and inhibiting the selection of inappropriate behavior. This inhibitory function involves multiple processes, such as reactive and proactive inhibition, instead of a...
9.
Terao Y, Nomura Y, Fukuda H, Hikosaka O, Kimura K, Matsuda S, et al.
Brain Sci
. 2023 Dec;
13(12).
PMID: 38137082
Aim: To elucidate the pathophysiology of Gilles de la Tourette syndrome (GTS), which is associated with prior use of dopamine receptor antagonists (blockers) and treatment by L-Dopa, through saccade performance....
10.
Terao Y, Fukuda H, Hikosaka O, Yugeta A, Matsuda S, Fisicaro F, et al.
Clin Neurophysiol
. 2023 Dec;
157:73-87.
PMID: 38064930
Objective: To investigate the oculomotor manifestations of Segawa disease (SD), considered to represent mild dopamine deficiency and discuss their pathophysiological basis. Methods: We recorded visually- (VGS) and memory-guided saccade (MGS)...