Oezcan Talay
Overview
Explore the profile of Oezcan Talay including associated specialties, affiliations and a list of published articles.
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10
Citations
285
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0
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Recent Articles
1.
Jorapur A, Marshall L, Jacobson S, Xu M, Marubayashi S, Zibinsky M, et al.
PLoS Pathog
. 2022 Jan;
18(1):e1010200.
PMID: 35025968
The Epstein-Barr Virus (EBV) is involved in the etiology of multiple hematologic and epithelial human cancers. EBV+ tumors employ multiple immune escape mechanisms, including the recruitment of immunosuppressive regulatory T...
2.
Marshall L, Marubayashi S, Jorapur A, Jacobson S, Zibinsky M, Robles O, et al.
J Immunother Cancer
. 2020 Nov;
8(2).
PMID: 33243932
Background: Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But...
3.
Robles O, Jackson J, Marshall L, Talay O, Chian D, Cutler G, et al.
J Med Chem
. 2020 Jul;
63(15):8584-8607.
PMID: 32667798
The C-C chemokine receptor 4 (CCR4) is broadly expressed on regulatory T cells (T) as well as other circulating and tissue-resident T cells. T can be recruited to the tumor...
4.
Jackson J, Ketcham J, Younai A, Abraham B, Biannic B, Beck H, et al.
J Med Chem
. 2019 Jul;
62(13):6190-6213.
PMID: 31259550
Recruitment of suppressive CD4 FOXP3 regulatory T cells (T) to the tumor microenvironment (TME) has the potential to weaken the antitumor response in patients receiving treatment with immuno-oncology (IO) agents....
5.
Ketcham J, Marshall L, Talay O
ACS Med Chem Lett
. 2018 Oct;
9(10):953-955.
PMID: 30344896
Recruitment of naturally occurring suppressive CD4, CD25, and FOXP3 regulatory T cells (T) to the tumor microenvironment (TME) has the potential to weaken the antitumor response in patients receiving treatment...
6.
Talay O, Yan D, Brightbill H, Straney E, Zhou M, Ladi E, et al.
Nat Immunol
. 2013 Nov;
14(12):1302-4.
PMID: 24240161
No abstract available.
7.
Talay O, Yan D, Brightbill H, Straney E, Zhou M, Ladi E, et al.
Nat Immunol
. 2012 Feb;
13(4):396-404.
PMID: 22366892
Immunoglobulin E (IgE) antibodies are pathogenic in asthma and allergic diseases, but the in vivo biology of IgE-producing (IgE(+)) cells is poorly understood. A model of the differentiation of IgE(+)...
8.
Shen C, Talay O, Mahajan V, Leskov I, Eisen H, Chen J
Proc Natl Acad Sci U S A
. 2010 Dec;
107(52):22587-92.
PMID: 21149737
Memory T cells of the effector type (T(EM)) account for the characteristic rapidity of memory T-cell responses, whereas memory T cells of the central type (T(CM)) account for long-lasting, vigorously...
9.
Talay O, Shen C, Chen L, Chen J
Proc Natl Acad Sci U S A
. 2009 Feb;
106(8):2741-6.
PMID: 19202065
Studies have shown that T-cell-dendritic cell (DC) interaction is required for efficient DC maturation. However, the identities of the molecules that mediate the interaction in vivo are largely unknown. Here,...
10.
Shen C, Ge Q, Talay O, Eisen H, Garcia-Sastre A, Chen J
J Immunol
. 2007 Dec;
180(1):171-8.
PMID: 18097017
Following influenza virus infection, memory CD8 T cells are found in both lymphoid and nonlymphoid organs, where they exhibit striking differences in survival. We have assessed persistence, phenotype, and function...