Octavio Espinosa
Overview
Explore the profile of Octavio Espinosa including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
203
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Genetic Interactions and Tissue Specificity Modulate the Association of Mutations with Drug Response
Cramer D, Mazur J, Espinosa O, Schlesner M, Hubschmann D, Eils R, et al.
Mol Cancer Ther
. 2019 Dec;
19(3):927-936.
PMID: 31826931
In oncology, biomarkers are widely used to predict subgroups of patients that respond to a given drug. Although clinical decisions often rely on single gene biomarkers, machine learning approaches tend...
2.
Noll E, Eisen C, Stenzinger A, Espinet E, Muckenhuber A, Klein C, et al.
Nat Med
. 2016 Feb;
22(3):278-87.
PMID: 26855150
Although subtypes of pancreatic ductal adenocarcinoma (PDAC) have been described, this malignancy is clinically still treated as a single disease. Here we present patient-derived models representing the full spectrum of...
3.
Espinosa O, Mitsopoulos K, Hakas J, Pearl F, Zvelebil M
PLoS One
. 2014 Jan;
9(1):e84598.
PMID: 24454733
With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate...
4.
Espinosa O, Hancock J
PLoS One
. 2011 Jun;
6(5):e19693.
PMID: 21625554
The laboratory mouse is the pre-eminent model organism for the dissection of human disease pathways. With the advent of a comprehensive panel of gene knockouts, projects to characterise the phenotypes...
5.
Ainali C, Simon M, Freilich S, Espinosa O, Hazelwood L, Tsoka S, et al.
BMC Evol Biol
. 2011 May;
11:142.
PMID: 21612628
Background: Cellular ATP levels are generated by glucose-stimulated mitochondrial metabolism and determine metabolic responses, such as glucose-stimulated insulin secretion (GSIS) from the β-cells of pancreatic islets. We describe an analysis...
6.
Kriventseva E, Rahman N, Espinosa O, Zdobnov E
Nucleic Acids Res
. 2007 Oct;
36(Database issue):D271-5.
PMID: 17947323
The concept of orthology is widely used to relate genes across different species using comparative genomics, and it provides the basis for inferring gene function. Here we present the web...