Octavian Savu
Overview
Explore the profile of Octavian Savu including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
321
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Recent Articles
1.
Trandafir M, Savu O, Pasarica D, Bleotu C, Gheorghiu M
Med Sci (Basel)
. 2024 Jun;
12(2).
PMID: 38921685
Hemodialyzed patients have innate immunity activation and adaptive immunity senescence. Diabetes mellitus is a frequent cause for chronic kidney disease and systemic inflammation. We studied the immunological pattern (innate and...
2.
Stoian I, Iosif L, Gilca M, Vlad A, Tivig I, Bradescu O, et al.
Life (Basel)
. 2024 May;
14(5).
PMID: 38792578
: Type 2 diabetes mellitus (T2DM) is a major cardiovascular risk factor. Nitric oxide (NO) is one of the many molecules that regulate vascular tone, and red blood cells (RBCs)...
3.
Trandafir M, Gradisteanu Pircalabioru G, Savu O
Exp Ther Med
. 2024 Apr;
27(5):211.
PMID: 38590581
Chronic kidney disease (CKD) is a widespread health concern, which affects ~9.1% of the global population and 12-15% of individuals in upper-middle income countries. Notably, ~2% of patients with CKD...
4.
Gradisteanu Pircalabioru G, Grigore G, Czobor Barbu I, Chifiriuc M, Savu O
Biomedicines
. 2023 Jan;
11(1).
PMID: 36672688
The severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic has advanced our understanding of the host-microbiome-virus interplay. Several studies in various geographical regions report that SARS-CoV-2 infection disrupts the intestinal...
5.
Gradisteanu Pircalabioru G, Chifiriuc M, Picu A, Petcu L, Trandafir M, Savu O
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499348
The prevalence of type 2 diabetes mellitus (T2D) is alarmingly increasing worldwide, urgently calling for a better understanding of the underlying mechanisms in order to step up prevention and improve...
6.
Gradisteanu Pircalabioru G, Corcionivoschi N, Gundogdu O, Chifiriuc M, Marutescu L, Ispas B, et al.
Int J Mol Sci
. 2021 Apr;
22(5).
PMID: 33803255
Globally, we are facing a worrying increase in type 1 diabetes mellitus (T1DM) incidence, with onset at younger age shedding light on the need to better understand the mechanisms of...
7.
Picu A, Petcu L, Stefan D, Gradisteanu Pircalabioru G, Mitu M, Bajko D, et al.
Metabolites
. 2020 Aug;
10(8).
PMID: 32731443
Geography is one of the key drivers of the significant variation in the etiopathogenic profile and prevalence of type 2 diabetes mellitus (T2DM) and obesity, therefore geographically based data are...
8.
Xu C, Bentinger M, Savu O, Moshfegh A, Sunkari V, Dallner G, et al.
J Diabetes Complications
. 2016 Nov;
31(1):4-12.
PMID: 27839658
Diabetes mellitus is characterized by hyperglycemia and capillary hypoxia that causes excessive production of free radicals and impaired antioxidant defense, resulting in oxidative stress and diabetes complications such as impaired...
9.
Savu O, Elian V, Steriade O, Teodoru I, Mihut S, Tacu C, et al.
Int Urol Nephrol
. 2016 Jan;
48(2):265-70.
PMID: 26725077
Purpose: We aimed to analyze the impact of basal insulin analogues on glucose variability (GV) in patients with type 2 diabetes (DM) undergoing renal replacement therapy. Methods: Fourteen subjects on...
10.
Savu O, Iosif L, Bradescu O, Serafinceanu C, Papacocea R, Stoian I
Ann Clin Biochem
. 2014 Mar;
52(Pt 1):135-43.
PMID: 24675988
Background: We investigated the l-arginine (l-Arg)-nitric oxide (NO) metabolic pathway in the erythrocytes (RBCs) and plasma of subjects with type 2 diabetes at first clinical onset. Methods: RBCs and plasma...