O Rotzschke
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Explore the profile of O Rotzschke including associated specialties, affiliations and a list of published articles.
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47
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2333
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Recent Articles
1.
Andiappan A, Puan K, Lee B, Nardin A, Poidinger M, Connolly J, et al.
Allergy
. 2014 Jan;
69(4):501-9.
PMID: 24456108
Background: Southeast Asian populations are increasingly affected by allergic airway diseases. Etiology and specific causes, however, are still unknown. The aim of this study is therefore to identify allergens and...
2.
Stienekemeier M, Falk K, Rotzschke O, Weishaupt A, Schneider C, Toyka K, et al.
Proc Natl Acad Sci U S A
. 2001 Nov;
98(24):13872-7.
PMID: 11717443
Using a polypeptide oligomer harboring 16 repeats of the neuritogenic epitope (aa 58-73) of myelin P2 protein separated by spacers, enhancement of the immune response to the P2 protein, an...
3.
Mack J, Falk K, Rotzschke O, Walk T, Strominger J, Jung G
J Pept Sci
. 2001 Jul;
7(6):338-45.
PMID: 11461048
Polypeptide constructs containing up to four copies of the T cell epitope 306-318 of influenza virus haemagglutinin have been synthesized on solid phase. Between the copies, a non-natural PEG-based spacer...
4.
Falk K, Rotzschke O, Strominger J
Eur J Immunol
. 2000 Nov;
30(10):3012-20.
PMID: 11069085
In a previous study we reported that oligomerized T cell epitopes "superactivated" CD4+ T cells. These oligomers, consisting of 12-16 copies of a peptide epitope derived from the hemagglutinin protein...
5.
Falk K, Rotzschke O, Santambrogio L, Dorf M, Brosnan C, Strominger J
J Exp Med
. 2000 Feb;
191(4):717-30.
PMID: 10684863
T cell epitope peptides derived from proteolipid protein (PLP139-151) or myelin basic protein (MBP86-100) induce experimental autoimmune encephalomyelitis (EAE) in "susceptible" strains of mice (e.g., SJL/J). In this study, we...
6.
Rotzschke O, Falk K, Mack J, Lau J, Jung G, Strominger J
Proc Natl Acad Sci U S A
. 1999 Jun;
96(13):7445-50.
PMID: 10377434
Class II MHC molecules are known to exist in conformational variants. "Floppy" and "compact" forms of murine MHC molecules, for example, are discriminated by their migration behavior on SDS/PAGE and...
7.
Rotzschke O, Falk K, Strominger J
Proc Natl Acad Sci U S A
. 1998 Feb;
94(26):14642-7.
PMID: 9405666
The peptides bound to class II major histocompatibility complex (MHC) molecules extend out both ends of the peptide binding groove. This structural feature provided the opportunity to design multivalent polypeptide...
8.
Maryanski J, Casanova J, Falk K, Gournier H, Jaulin C, Kourilsky P, et al.
Hum Immunol
. 1997 May;
54(2):117-28.
PMID: 9297530
Antigen-selected T cell receptor (TCR) repertoires vary in complexity from very limited to extremely diverse. We have previously characterized two different CD8 T cell responses, which are restricted by the...
9.
Steinle A, Falk K, Rotzschke O, Gnau V, Stevanovic S, Jung G, et al.
Immunogenetics
. 1996 Jan;
43(1-2):105-7.
PMID: 8537112
No abstract available.
10.
Falk K, Rotzschke O, Takiguchi M, Gnau V, Stevanovic S, Jung G, et al.
Int Immunol
. 1995 Feb;
7(2):223-8.
PMID: 7734418
Here we report peptide motifs of five HLA-B molecules, B*5101, B*5102, B*5103 B*5201 and B*7801. Motifs were obtained by pool sequencing of natural ligands eluted from the respective molecules expressed...