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O Rosario

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Articles 10
Citations 153
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Recent Articles
1.
Alvarez-Aviles O, Cuadra-Rodriguez L, Gonzalez-Illan F, Quinones-Gonzalez J, Rosario O
Anal Chim Acta . 2007 Aug; 597(2):273-81. PMID: 17683739
A practical analytical methodology based on coupling microwave-assisted extraction-stir bar sorptive extraction-thermal desorption-gas chromatography-mass spectrometry (MAE-SBSE-TD-GC-MS) was developed and validated for the characterization of several SVOC in atmospheric particulate matter...
2.
Rodriguez J, Rodriguez J, SantAna J, Garcia H, Rosario O
Antimicrob Agents Chemother . 2000 Oct; 44(11):3097-100. PMID: 11036029
Highly active antiretroviral therapy (HAART) is the standard treatment for infection with human immunodeficiency virus (HIV). The most common HAART regimen consists of the combination of at least one protease...
3.
Colon I, Caro D, Bourdony C, Rosario O
Environ Health Perspect . 2000 Oct; 108(9):895-900. PMID: 11017896
Premature breast development (thelarche) is the growth of mammary tissue in girls younger than 8 years of age without other manifestations of puberty. Puerto Rico has the highest known incidence...
4.
Reyes D, Rosario O, Rodriguez J, Jimenez B
Environ Health Perspect . 2000 Jul; 108(7):635-40. PMID: 10903617
In recent years, several hypotheses have emerged to explain the toxicologic activity of particulate matter. Organic compounds, ultrafine particles, biologic components, and transition metals are some of the constituents that...
5.
Rodriguez Orengo J, SantAna J, Febo I, Diaz C, Rodriguez J, Garcia R, et al.
P R Health Sci J . 2000 Apr; 19(1):19-27. PMID: 10761201
Nucleoside reverse transcriptase inhibitors (NRTIs) plasma concentrations do not correlate with clinical efficacy or toxicity. These agents need to be phosphorylated to become active against HIV-infection. Thus, the characterization of...
6.
Font E, Rosario O, SantAna J, Garcia H, Sommadossi J, Rodriguez J
Antimicrob Agents Chemother . 1999 Dec; 43(12):2964-8. PMID: 10582890
Nucleoside reverse transcriptase inhibitors (NRTIs) used against the human immunodeficiency virus (HIV) need to be activated intracellularly to their triphosphate moiety to inhibit HIV replication. Intracellular concentrations of these NRTI...
7.
Figueroa I, el Baraka M, Quinones E, Rosario O, DEUMIE M
Anal Chem . 1998 Sep; 70(18):3974-7. PMID: 9751031
A temperature probe based on the fluorescence properties of the two excited states of 4-(N,N-dimethylamino)benzonitrile (DMABN) in equilibrium with beta-cyclodextrin (CD) in aqueous solution is presented. The fluorescence intensity of...
8.
Font E, Lasanta S, Rosario O, Rodriguez J
Nucleosides Nucleotides . 1998 Aug; 17(5):845-53. PMID: 9708327
Antiretroviral nucleoside drugs used against the human immunodeficiency virus (HIV) infection have been analyzed using negative ion electrospray ionization (ESI) mass spectrometry and collision-induced dissociation (CID-MS/MS). Mass fragmentation of azidothymidine...
9.
Almodovar R, Rodriguez R, Rosario O
J Pharm Biomed Anal . 1998 Aug; 17(1):89-93. PMID: 9696597
The use of supercritical CO2 for the isolation of acetaminophen from the non-polar matrix of a suppository is demonstrated. Since acetaminophen is not soluble in pure CO2 at low pressure,...
10.
Bloom J, Lehman P, Israel M, Rosario O, Korfmacher W
J Anal Toxicol . 1992 Jul; 16(4):223-7. PMID: 1501475
Mass spectral results for three anthracyclines, doxorubicin, daunorubicin, and carminomycin are compared by using thermospray (TS) or particle beam (PB) [electron ionization (EI) and chemical ionization (CI)] instruments. Typically, positive...