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O J Billington

Explore the profile of O J Billington including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 182
Followers 0
Related Specialties
Microbiology
Infectious Diseases
General Medicine
Top 10 Co-Authors
S H Gillespie
T D McHugh
A P Davies
L O Neville
S Patel
C F Pope
D A Mitchison
B A Bannister
M C Lipman
R D Gosling
Published In
J Infect
Lancet
J Clin Microbiol
Antimicrob Agents Chemother
J Med Microbiol
Affiliations
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Recent Articles
1.
Estimation of mutation rates in antibiotic research
Billington O, Gillespie S
Methods Mol Med . 2011 Mar; 48:227-32. PMID: 21374422
Luria and Delbruck identified that the frequency of mutation was subject to considerable fluctuation. They argued that the large fluctuation in the number of organism surviving exposure to bacteriophage meant...
2.
Prospective evaluation of BDProbeTec strand displacement amplification (SDA) system for diagnosis of tuberculosis in non-respiratory and respiratory samples
McHugh T, Pope C, Ling C, Patel S, Billington O, Gosling R, et al.
J Med Microbiol . 2004 Dec; 53(Pt 12):1215-1219. PMID: 15585500
Nucleic acid amplification techniques (NAATs) have been demonstrated to make significant improvements in the diagnosis of tuberculosis (TB), particularly in the time to diagnosis and the diagnosis of smear-negative TB....
3.
Comparison of fitness of two isolates of Mycobacterium tuberculosis, one of which had developed multi-drug resistance during the course of treatment
Davies A, Billington O, Bannister B, Weir W, McHugh T, Gillespie S
J Infect . 2000 Oct; 41(2):184-7. PMID: 11023769
Objectives: We report the cases of two patients, brother and sister, both with pulmonary tuberculosis. Both patients complied poorly with treatment. One developed multi-drug resistant disease, whilst the other did...
4.
Comparison of phenotypic and genotypic methods for pyrazinamide susceptibility testing with Mycobacterium tuberculosis
Davies A, Billington O, McHugh T, Mitchison D, Gillespie S
J Clin Microbiol . 2000 Oct; 38(10):3686-8. PMID: 11015384
Mycobacterium tuberculosis converts pyrazinamide to its active form by using the enzyme pyrazinamidase. This enzyme is coded for on the pncA gene, and mutations in the pncA gene result in...
5.
Length of time to laboratory diagnosis of Mycobacterium tuberculosis infection: comparison of in-house methods with reference laboratory results
Davies A, Newport L, Billington O, Gillespie S
J Infect . 2000 Mar; 39(3):205-8. PMID: 10714796
Objectives: To audit the time taken to obtain laboratory confirmation of infection with Mycobacterium tuberculosis using in-house methods of polymerase chain reaction (PCR) and culture and referral to a reference...
6.
Physiological cost of rifampin resistance induced in vitro in Mycobacterium tuberculosis
Billington O, McHugh T, Gillespie S
Antimicrob Agents Chemother . 1999 Aug; 43(8):1866-9. PMID: 10428904
Drug-resistant Mycobacterium tuberculosis is a major threat to public health. In clinical practice, a limited number of resistance mutations in a short sequence of the beta subunit of RNA polymerase...
7.
Methicillin resistant Staphylococcus aureus without clumping factor, protein A, and DNAse
Neville L, Billington O, Kibbler C, Gillespie S
Lancet . 1991 Aug; 338(8765):518. PMID: 1678480
No abstract available.