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O E Michaelis 4th

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Citations 280
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11.
Robison Jr W, McCaleb M, Feld L, Michaelis 4th O, Laver N, Mercandetti M, et al.
Curr Eye Res . 1991 Apr; 10(4):339-50. PMID: 1829996
One of the earliest histopathological signs of diabetic retinopathy is a selective loss of intramural pericytes from retinal capillaries. In the present study, the retinal vessels of rats with streptozotocin-induced...
12.
Tulp O, Hansen C, McKee K, Michaelis 4th O
Comp Biochem Physiol A Comp Physiol . 1991 Jan; 99(3):457-62. PMID: 1678339
1. Groups of lean and obese male SHR/N-cp rats were fed isoenergetic diets containing 54% carbohydrate as cornstarch (CS) or sucrose (SU) plus other nutrients from 5 weeks of age,...
13.
Tulp O, Szepesi B, Michaelis 4th O, DeBouno Jr J
Comp Biochem Physiol C Comp Pharmacol Toxicol . 1991 Jan; 99(1-2):241-6. PMID: 1675969
1. Groups of lean, obese, and obese-non-insulin-dependent diabetic LA/N-cp and SHR/N-cp rats were administered the a-glucosidase inhibitor Miglitol (150 mg/kg diet, ad libitum) from 8 until 15 weeks of age....
14.
Tulp O, DeBolt S, Hansen C, Michaelis 4th O
Comp Biochem Physiol A Comp Physiol . 1991 Jan; 99(1-2):229-34. PMID: 1675951
1. Adipose mass and cellularity were studied in congenic female SHR/N-cp rats fed iosenergetic diets containing 54% carbohydrate as sucrose (SU) or cooked cornstarch (CS), 20% protein, 16% mixed dietary...
15.
Michaelis 4th O, Carswell N, Velasquez M, Kimmel P, Abraham A, CANARY J, et al.
Int J Obes . 1990 Nov; 14(11):973-85. PMID: 2177455
Young female obese (cp/cp) and lean littermates (?/+) of the recently developed congenic strain, SHR/NIH-corpulent (SHR/N-cp), were fed for 6.5 months isocaloric diets containing 54 percent carbohydrate as either sucrose...
16.
Velasquez M, Kimmel P, Michaelis 4th O
FASEB J . 1990 Aug; 4(11):2850-9. PMID: 2199283
Kidney disease, characterized by proteinuria and glomerular lesions, is a common complication of spontaneous diabetes mellitus in many animal species. It occurs in animals with hypoinsulinemia, hyperinsulinemia, or impaired glucose...
17.
Lewis C, Michaelis 4th O, Yang C, Carswell N
J Am Coll Nutr . 1989 Dec; 8(6):608-16. PMID: 2482846
A new rodent model, SHR/N-cp, for study of non-insulin-dependent diabetes mellitus (NIDDM) has recently been developed. The present study reports exocrine pancreatic enzyme activities and mineral concentrations in female corpulent...
18.
Bhathena S, Kennedy B, Jones J, Smith P, Michaelis 4th O, Carswell N, et al.
Proc Soc Exp Biol Med . 1989 Oct; 192(1):66-71. PMID: 2552455
A new congenic strain of rat, the SHR/N-corpulent, provides a good model for noninsulin-dependent diabetes and was used in the present study. Corpulent rats as compared to their lean littermates...
19.
Velasquez M, Kimmel P, Michaelis 4th O, Carswell N, ABraham A, Bosch J
Diabetes . 1989 Jun; 38(6):679-85. PMID: 2721822
The SHR/N corpulent (cp) rat is a genetically obese rat that develops hyperglycemia, hyperinsulinemia, and proteinuria. This study was designed to evaluate the effects of high carbohydrate (CHO) intake on...
20.
RECANT L, Voyles N, Timmers K, Bhathena S, Solomon D, Wilkins S, et al.
Diabetes . 1989 Jun; 38(6):691-7. PMID: 2656338
Obese diabetic SHR/N-(cp/cp) rats are a genetic model for non-insulin-dependent diabetes mellitus. When SHR/N-cp rats are overtly diabetic, they are hyperinsulinemic and hyperglycemic in the fed state when consuming commercial...