Nynke J van den Hoogen
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Explore the profile of Nynke J van den Hoogen including associated specialties, affiliations and a list of published articles.
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21
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93
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Recent Articles
1.
Fan C, McAllister B, Stokes-Heck S, Harding E, Pereira de Vasconcelos A, Mah L, et al.
Neuron
. 2025 Feb;
PMID: 39892387
Chronic pain is a leading cause of disability, affecting more women than men. Different immune cells contribute to this sexual divergence, but the mechanisms, especially in females, are not well...
2.
Ten Barge J, van den Bosch G, Slater R, van den Hoogen N, Reiss I, Simons S
Paediatr Drugs
. 2025 Jan;
27(2):201-220.
PMID: 39752054
Necrotizing enterocolitis (NEC) is a relatively rare but very severe gastrointestinal disease primarily affecting very preterm infants. NEC is characterized by excessive inflammation and ischemia in the intestines, and is...
3.
Kwok C, Harding E, Burma N, Markovic T, Massaly N, van den Hoogen N, et al.
Nat Commun
. 2024 Jul;
15(1):6264.
PMID: 39048565
Opioid withdrawal is a liability of chronic opioid use and misuse, impacting people who use prescription or illicit opioids. Hyperactive autonomic output underlies many of the aversive withdrawal symptoms that...
4.
Parisien M, van Reij R, Khoury S, Koseli E, Karaky M, Silva J, et al.
Br J Anaesth
. 2024 Jun;
133(2):360-370.
PMID: 38862382
Background: Chronic post-surgical pain (CPSP) significantly impacts patients' recovery and quality of life. Although environmental risk factors are well-established, genetic risk remains less understood. Methods: A meta-analysis of genome-wide association...
5.
McAllister B, Stokes-Heck S, Harding E, van den Hoogen N, Trang T
CNS Drugs
. 2024 Feb;
38(2):77-91.
PMID: 38353876
Chronic pain complicates many diseases and is notoriously difficult to treat. In search of new therapeutic targets, pannexin-1 (Panx1) channels have sparked intense interest as a key mechanism involved in...
6.
Parisien M, van Reij R, Khoury S, Koseli E, Karaky M, van den Hoogen N, et al.
medRxiv
. 2023 Mar;
PMID: 36945481
Chronic post-surgical pain affects a large proportion of people undergoing surgery, delaying recovery time and worsening quality of life. Although many environmental variables have been established as risk factors, less...
7.
de Kort A, Joosten E, Patijn J, Tibboel D, van den Hoogen N
Front Pain Res (Lausanne)
. 2022 May;
3:872587.
PMID: 35571143
Neonatal painful procedures causes acute pain and trigger long-term changes in nociceptive processing and anxiety behavior, highlighting the need for adequate analgesia during this critical time. Spinal serotonergic receptors 5-HT1a...
8.
de Kort A, Joosten E, Versantvoort E, Patijn J, Tibboel D, van den Hoogen N
Int J Dev Neurosci
. 2022 Apr;
82(4):361-371.
PMID: 35393725
Excessive noxious stimulation during the critical neonatal period impacts the nociceptive network lasting into adulthood. As descending serotonergic projections from the rostral ventromedial medulla (RVM) to the spinal dorsal horn...
9.
van den Hoogen N, Harding E, Davidson C, Trang T
Front Neural Circuits
. 2022 Jan;
15:816747.
PMID: 35069129
Chronic pain is a complex sensory, cognitive, and emotional experience that imposes a great personal, psychological, and socioeconomic burden on patients. An estimated 1.5 billion people worldwide are afflicted with...
10.
de Kort A, Joosten E, Patijn J, Tibboel D, van den Hoogen N
Dev Psychobiol
. 2021 Nov;
63(8):e22210.
PMID: 34813103
The influence of neonatal experiences upon later-life affective behavior is increasingly recognized, but the reported effects on anxiety are often contradictory. The observed effect may depend upon the type of...