Nutan Prasain
Overview
Explore the profile of Nutan Prasain including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
623
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0
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Recent Articles
1.
Lin Y, Gil C, Banno K, Yokoyama M, Wingo M, Go E, et al.
Circulation
. 2024 Apr;
150(6):451-465.
PMID: 38682338
Background: Most organs are maintained lifelong by resident stem/progenitor cells. During development and regeneration, lineage-specific stem/progenitor cells can contribute to the growth or maintenance of different organs, whereas fully differentiated...
2.
Lin Y, Banno K, Gil C, Myslinski J, Hato T, Shelley W, et al.
JCI Insight
. 2023 Jan;
8(5).
PMID: 36692963
Most circulating endothelial cells are apoptotic, but rare circulating endothelial colony-forming cells (C-ECFCs), also known as blood outgrowth endothelial cells, with proliferative and vasculogenic activity can be cultured; however, the...
3.
Gil C, Chakraborty D, Vieira C, Prasain N, Li Calzi S, Fortmann S, et al.
Sci Adv
. 2022 Mar;
8(9):eabm5559.
PMID: 35245116
Human induced pluripotent stem cells (hiPSCs) were differentiated into a specific mesoderm subset characterized by KDRCD56APLNR (KNA) expression. KNA cells had high clonal proliferative potential and specification into endothelial colony-forming...
4.
Fraineau S, Palii C, McNeill B, Ritso M, Shelley W, Prasain N, et al.
Stem Cell Reports
. 2017 Oct;
9(5):1573-1587.
PMID: 29033304
Human endothelial colony-forming cells (ECFCs) represent a promising source of adult stem cells for vascular repair, yet their regenerative capacity is limited. Here, we set out to understand the molecular...
5.
Moldovan L, Barnard A, Gil C, Lin Y, Grant M, Yoder M, et al.
Biotechnol J
. 2017 Oct;
12(12).
PMID: 29030959
Recently a protocol is established to obtain large quantities of human induced pluripotent stem cells (iPSC)-derived endothelial progenitors, called endothelial colony forming cells (ECFC), and of candidate smooth-muscle forming cells...
6.
Park S, Lee S, Prasain N, Bae D, Kang H, Ha T, et al.
Stem Cells Dev
. 2017 Mar;
26(10):734-742.
PMID: 28346802
Acquisition of proper metabolomic fate is required to convert somatic cells toward fully reprogrammed pluripotent stem cells. The majority of induced pluripotent stem cells (iPSCs) are partially reprogrammed and have...
7.
Kim H, Prasain N, Vemula S, Ferkowicz M, Yoshimoto M, Voytik-Harbin S, et al.
Microvasc Res
. 2015 Jul;
101:72-81.
PMID: 26122935
Human cord blood (CB) is enriched in circulating endothelial colony forming cells (ECFCs) that display high proliferative potential and in vivo vessel forming ability. Since diminished ECFC survival is known...
8.
Prasain N, Lee M, Vemula S, Meador J, Yoshimoto M, Ferkowicz M, et al.
Nat Biotechnol
. 2014 Oct;
32(11):1151-1157.
PMID: 25306246
The ability to differentiate human pluripotent stem cells into endothelial cells with properties of cord-blood endothelial colony-forming cells (CB-ECFCs) may enable the derivation of clinically relevant numbers of highly proliferative...
9.
Stevens T, Ochoa C, Morrow K, Robson M, Prasain N, Zhou C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2014 Apr;
306(10):L915-24.
PMID: 24705722
Exoenzyme Y (ExoY) is a Pseudomonas aeruginosa toxin that is introduced into host cells through the type 3 secretion system (T3SS). Once inside the host cell cytoplasm, ExoY generates cyclic...
10.
Balczon R, Prasain N, Ochoa C, Prater J, Zhu B, Alexeyev M, et al.
PLoS One
. 2013 Sep;
8(9):e74343.
PMID: 24023939
Pseudomonas aeruginosa uses a type III secretion system to introduce the adenylyl and guanylyl cyclase exotoxin Y (ExoY) into the cytoplasm of endothelial cells. ExoY induces Tau hyperphosphorylation and insolubility,...