Nuruddin Unchwaniwala
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Explore the profile of Nuruddin Unchwaniwala including associated specialties, affiliations and a list of published articles.
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9
Citations
120
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Recent Articles
1.
Romero S, Unchwaniwala N, Evans 3rd E, Eliceiri K, Loeb D, Sherer N
mBio
. 2023 Feb;
14(2):e0330322.
PMID: 36809075
Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress pathway. To better define sites of...
2.
Zhan H, Unchwaniwala N, Rebolledo-Viveros A, Pennington J, Horswill M, Broadberry R, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(5):e2217412120.
PMID: 36693094
Positive-strand RNA viruses replicate their genomes in virus-induced membrane vesicles, and the resulting RNA replication complexes are a major target for virus control. Nodavirus studies first revealed viral RNA replication...
3.
den Boon J, Zhan H, Unchwaniwala N, Horswill M, Slavik K, Pennington J, et al.
Viruses
. 2022 Dec;
14(12).
PMID: 36560715
Positive-strand RNA virus RNA genome replication occurs in membrane-associated RNA replication complexes (RCs). Nodavirus RCs are outer mitochondrial membrane invaginations whose necked openings to the cytosol are "crowned" by a...
4.
Nishikiori M, den Boon J, Unchwaniwala N, Ahlquist P
Annu Rev Virol
. 2022 May;
9(1):193-212.
PMID: 35610038
Positive-strand RNA viruses, the largest genetic class of eukaryotic viruses, include coronaviruses and many other established and emerging pathogens. A major target for understanding and controlling these viruses is their...
5.
Unchwaniwala N, Zhan H, den Boon J, Ahlquist P
Curr Opin Virol
. 2021 Oct;
51:74-79.
PMID: 34601307
The nodavirus flock house virus recently provided a well-characterized model for the first cryo-electron microscope tomography of membrane-bound, positive-strand RNA ((+)RNA) virus genome replication complexes (RCs). The resulting first views...
6.
Unchwaniwala N, Ahlquist P
Science
. 2020 Sep;
369(6509):1306-1307.
PMID: 32913092
No abstract available.
7.
Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon J, Ahlquist P
Proc Natl Acad Sci U S A
. 2020 Jul;
117(31):18680-18691.
PMID: 32690711
For positive-strand RNA [(+)RNA] viruses, the major target for antiviral therapies is genomic RNA replication, which occurs at poorly understood membrane-bound viral RNA replication complexes. Recent cryoelectron microscopy (cryo-EM) of...
8.
Unchwaniwala N, Sherer N, Loeb D
J Virol
. 2016 Jul;
90(19):8705-19.
PMID: 27440888
Unlabelled: To understand subcellular sites of hepatitis B virus (HBV) replication, we visualized core (Cp), polymerase (Pol), and pregenomic RNA (pgRNA) in infected cells. Interestingly, we found that the majority...
9.
Tan Z, Pionek K, Unchwaniwala N, Maguire M, Loeb D, Zlotnick A
J Virol
. 2015 Jan;
89(6):3275-84.
PMID: 25568211
Unlabelled: Hepatitis B virus (HBV) capsid proteins (Cps) assemble around the pregenomic RNA (pgRNA) and viral reverse transcriptase (P). pgRNA is then reverse transcribed to double-stranded DNA (dsDNA) within the...