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Nubia Silva

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Articles 7
Citations 55
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Recent Articles
1.
Mitchell J, Spanier J, Dwyer A, Knutson T, Alkhatib M, Qian G, et al.
Immunity . 2024 Aug; 57(10):2399-2415.e8. PMID: 39214091
T cell-mediated islet destruction is a hallmark of autoimmune diabetes. Here, we examined the dynamics and pathogenicity of CD4 T cell responses to four different insulin-derived epitopes during diabetes initiation...
2.
Pinheiro S, Silva C, Luiz L, Silva N, Fonseca R, Velasquez T, et al.
J Clin Pediatr Dent . 2023 Nov; 47(6):38-43. PMID: 37997233
Anxiety is common in pediatric dental care, and affects the behavioral management of children. Animal-assisted therapy (AAT) has been shown to improve children's behavior. However, few studies have applied this...
3.
Spanier J, Fung V, Wardell C, Alkhatib M, Chen Y, Swanson L, et al.
J Clin Invest . 2023 Aug; 133(18). PMID: 37561596
Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type 1 diabetes. Islet antigen-specific Tregs have more potent therapeutic effects than polyclonal cells, but their low frequency...
4.
Spanier J, Fung V, Wardell C, Alkhatib M, Chen Y, Swanson L, et al.
bioRxiv . 2023 Mar; PMID: 36865264
Brief Summary: Chimeric antigen receptor Tregs specific for an insulin B-chain peptide presented by MHC class II prevent autoimmune diabetes.
5.
Dwyer A, Ritz J, Mitchell J, Martinov T, Alkhatib M, Silva N, et al.
Sci Rep . 2021 Aug; 11(1):17142. PMID: 34433860
The notion that T cell insulitis increases as type 1 diabetes (T1D) develops is unsurprising, however, the quantitative analysis of CD4 and CD8 T cells within the islet mass is...
6.
Gabaldon-Figueira J, Salmen S, Silva N, Mancilla B, Vielma S
Trans R Soc Trop Med Hyg . 2019 Dec; 114(2):131-136. PMID: 31804686
Background: Malaria is expanding rapidly across Venezuela, spreading outwards from traditional high transmission regions in the southeast of the country, but the lack of official data make it impossible to...
7.
Bianchi F, Cucunuba Z, Guhl F, Gonzalez N, Freilij H, Nicholls R, et al.
PLoS Negl Trop Dis . 2015 Feb; 9(2):e0003465. PMID: 25723465
Background: Chagas disease is an anthropozoonosis caused by Trypanosoma cruzi. Two drugs are currently used for the etiological treatment of the disease: Nifurtimox (Lampit) and Benznidazole. This study presents a...