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Norman L Mack

Explore the profile of Norman L Mack including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Lago C, Federico A, Leva G, Mack N, Schwalm B, Ballabio C, et al.
EMBO Mol Med . 2023 Dec; 15(12):e18199. PMID: 38037472
Brain tumors are the leading cause of cancer-related death in children. Experimental in vitro models that faithfully capture the hallmarks and tumor heterogeneity of pediatric brain cancers are limited and...
2.
Krausert S, Brabetz S, Mack N, Schmitt-Hoffner F, Schwalm B, Peterziel H, et al.
Neurooncol Adv . 2022 Apr; 4(1):vdac026. PMID: 35475274
Background: Inhibition of the sonic hedgehog (SHH) pathway with Smoothened (SMO) inhibitors is a promising treatment strategy in SHH-activated medulloblastoma, especially in adult patients. However, the problem is that tumors...
3.
Brabetz S, Leary S, Grobner S, Nakamoto M, Seker-Cin H, Girard E, et al.
Nat Med . 2018 Oct; 24(11):1752-1761. PMID: 30349086
Brain tumors are the leading cause of cancer-related death in children. Genomic studies have provided insights into molecular subgroups and oncogenic drivers of pediatric brain tumors that may lead to...