Noriko Saito-Tarashima
Overview
Explore the profile of Noriko Saito-Tarashima including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
55
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Hinotani N, Saito-Tarashima N, Minakawa N
Curr Protoc
. 2021 Nov;
1(11):e297.
PMID: 34837670
A convenient synthetic method for preparing 3-deazapurine nucleosides (3-deazainosine, 3-deazaadenosine, and 3-deazaguanosine) from inosine via a 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide (EICAR) derivative, which is a key intermediate, is described. A large-scale synthesis of...
12.
Saito-Tarashima N, Kinoshita M, Igata Y, Kashiwabara Y, Minakawa N
RSC Med Chem
. 2021 Oct;
12(9):1519-1524.
PMID: 34671735
Cyclic dinucleotides (CDNs) are secondary messengers composed of two purine nucleotides linked two phosphodiester linkages: c-di-GMP, c-di-AMP, 3',3'-cGAMP, and 2',3'-cGAMP. CDNs activate the stimulator of interferon genes (STING) and trigger...
13.
Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, et al.
iScience
. 2021 Sep;
24(10):103120.
PMID: 34541466
Newly emerging or re-emerging viral infections continue to cause significant morbidity and mortality every year worldwide, resulting in serious effects on both health and the global economy. Despite significant drug...
14.
Maeda R, Saito-Tarashima N, Wakamatsu H, Natori Y, Minakawa N, Yoshimura Y
Org Lett
. 2021 May;
23(10):4062-4066.
PMID: 33938754
To develop a new nucleoside analogue applicable to oligonucleotide therapeutics, we designed a 4'-thio analogue of an LNA/BNA monomer. Synthesis of 4'-hydroxymethyl-4'-thioribonucleoside was achieved by a tandem ring-contraction-aldol reaction of...
15.
Saito-Tarashima N
Yakugaku Zasshi
. 2020 Oct;
140(10):1259-1268.
PMID: 32999205
RNA interference (RNAi) is the standard method of suppressing gene expression because of its target specificity, potency, and ability to silence the expression of virtually any gene. Using 21-mer small...
16.
Ando H, Saito-Tarashima N, Lila A, Kinjo N, Shimizu T, Ishima Y, et al.
Molecules
. 2020 Apr;
25(7).
PMID: 32283709
Background: We have recently introduced an intelligent RNA expression device (iRed), comprising the minimum essential components needed to transcribe short hairpin RNA (shRNA) in cells. Use of iRed efficiently produced...
17.
Matsumoto K, Saito-Tarashima N, Wada T, Yonaha O, Minakawa N
Nucleosides Nucleotides Nucleic Acids
. 2020 Jan;
41(10):943-960.
PMID: 31994434
Furanopyrimidine (FPy) and 2,6-diamino-3-deazapurine (DCPu) nucleosides with the ability to interact in DDD and AAA H-bonding patterns, respectively, were prepared. The N-1 p value of the DCPu nucleoside was estimated...
18.
Okano Y, Saito-Tarashima N, Kurosawa M, Iwabu A, Ota M, Watanabe T, et al.
Bioorg Med Chem
. 2019 Apr;
27(11):2181-2186.
PMID: 31003866
In this work, we developed imidazole nucleoside derivatives with anti-dengue virus (DENV) activity was examined. First, compounds in a nucleosides library were screened to find lead compounds which inhibit replication...
19.
Anindita P, Sasaki M, Okada K, Ito N, Sugiyama M, Saito-Tarashima N, et al.
Antiviral Res
. 2018 Mar;
154:1-9.
PMID: 29601893
Rabies remains an invariably fatal neurological disease despite the availability of a preventive vaccination and post-exposure prophylaxis that must be immediately administered to the exposed individual before symptom onset. There...
20.
Saito-Tarashima N, Minakawa N
Chem Pharm Bull (Tokyo)
. 2018 Feb;
66(2):132-138.
PMID: 29386463
In this review, we have summarized the research effort into the development of unnatural base pairs beyond standard Watson-Crick (WC) base pairs for synthetic biology. Prior to introducing our research...