Noriko Kane-Goldsmith
Overview
Explore the profile of Noriko Kane-Goldsmith including associated specialties, affiliations and a list of published articles.
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18
Citations
706
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Recent Articles
1.
Vazquez B, Thackray J, Simonet N, Chahar S, Kane-Goldsmith N, Newkirk S, et al.
Nucleic Acids Res
. 2019 Jun;
47(15):7870-7885.
PMID: 31226208
Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of self-propagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how this process...
2.
Bosch-Presegue L, Raurell-Vila H, Thackray J, Gonzalez J, Casal C, Kane-Goldsmith N, et al.
Cell Rep
. 2017 Nov;
21(8):2048-2057.
PMID: 29166597
HP1 is a structural component of heterochromatin. Mammalian HP1 isoforms HP1α, HP1β, and HP1γ play different roles in genome stability, but their precise role in heterochromatin structure is unclear. Analysis...
3.
Raurell-Vila H, Bosch-Presegue L, Gonzalez J, Kane-Goldsmith N, Casal C, Brown J, et al.
Epigenetics
. 2017 Jan;
12(2):166-175.
PMID: 28059589
The presence of H3K9me3 and heterochromatin protein 1 (HP1) are hallmarks of heterochromatin conserved in eukaryotes. The spreading and maintenance of H3K9me3 is effected by the functional interplay between the...
4.
Vazquez B, Thackray J, Simonet N, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, et al.
EMBO J
. 2016 May;
35(14):1488-503.
PMID: 27225932
Sirtuins, a family of protein deacetylases, promote cellular homeostasis by mediating communication between cells and environment. The enzymatic activity of the mammalian sirtuin SIRT7 targets acetylated lysine in the N-terminal...
5.
Tereshchenko I, Zhong H, Chekmareva M, Kane-Goldsmith N, Santanam U, Petrosky W, et al.
Prostate
. 2014 Sep;
74(15):1551-9.
PMID: 25175909
Background: Biomarkers predicting tumor response are important to emerging targeted therapeutics. Complimentary methods to assess and understand genetic changes and heterogeneity within only few cancer cells in tissue will be...
6.
Serrano L, Martinez-Redondo P, Marazuela-Duque A, Vazquez B, Dooley S, Voigt P, et al.
Genes Dev
. 2013 Mar;
27(6):639-53.
PMID: 23468428
The establishment of the epigenetic mark H4K20me1 (monomethylation of H4K20) by PR-Set7 during G2/M directly impacts S-phase progression and genome stability. However, the mechanisms involved in the regulation of this...
7.
Martel G, Hevi C, Kane-Goldsmith N, Shumyatsky G
Behav Brain Res
. 2011 May;
223(1):233-8.
PMID: 21545813
Since zinc transporter ZnT3 is localized to the hippocampus and perirhinal cortex, we used ZnT3 knockout mice (KO) to analyze the role of ZnT3 in memory and behavior dependent on...
8.
Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection
Bosch-Presegue L, Raurell-Vila H, Marazuela-Duque A, Kane-Goldsmith N, Valle A, Oliver J, et al.
Mol Cell
. 2011 Apr;
42(2):210-23.
PMID: 21504832
Sirtuins are NAD-dependent deacetylases that sense oxidative stress conditions and promote a protective cellular response. The Sirtuin SirT1 is involved in facultative heterochromatin formation through an intimate functional relationship with...
9.
Otsuka S, Adamson C, Sankar V, Gibbs K, Kane-Goldsmith N, Ayer J, et al.
J Neurotrauma
. 2011 Mar;
28(6):1063-76.
PMID: 21443453
RhoA is a key regulator of the actin cytoskeleton that is upregulated after spinal cord injury (SCI). We analyzed different methods for siRNA delivery and developed siRNAs targeting RhoA (siRhoA)...
10.
Babiarz J, Kane-Goldsmith N, Basak S, Liu K, Young W, Grumet M
Exp Neurol
. 2010 Sep;
229(1):72-9.
PMID: 20850435
Olfactory ensheathing cells (OEC), which normally associate closely with but do not myelinate axons in situ, myelinate axons in the adult mammalian spinal cord. They are of clinical interest as...