Norihisa Mikami
Overview
Explore the profile of Norihisa Mikami including associated specialties, affiliations and a list of published articles.
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28
Citations
924
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Recent Articles
1.
Yasumizu Y, Takeuchi D, Morimoto R, Takeshima Y, Okuno T, Kinoshita M, et al.
Cell Genom
. 2024 Feb;
4(2):100473.
PMID: 38359792
CD4 T cells are key mediators of various autoimmune diseases; however, their role in disease progression remains unclear due to cellular heterogeneity. Here, we evaluated CD4 T cell subpopulations using...
2.
3.
Mikami N, Sakaguchi S
Nat Rev Nephrol
. 2023 Jul;
19(9):544-557.
PMID: 37400628
Regulatory T (T) cells that express the transcription factor forkhead box protein P3 (FOXP3) are naturally present in the immune system and have roles in the maintenance of immunological self-tolerance...
4.
Sakaguchi S, Kawakami R, Mikami N
Immunother Adv
. 2023 Jul;
3(1):ltad007.
PMID: 37397971
FoxP3-expressing regulatory T cells (Tregs), whether naturally generated in the immune system or unnaturally induced from conventional T cells (Tconvs) in the laboratory, have much therapeutic value in treating immunological...
5.
Nakano S, Mikami N, Miyawaki M, Yamasaki S, Miyamoto S, Yamada M, et al.
Biol Pharm Bull
. 2022 May;
45(8):1053-1060.
PMID: 35613869
Combination treatment using fingolimod (FTY720), an immunomodulator, and a pathogenic antigen prevents the progression of glucose-6-phosphate isomerase (GPI)-induced arthritis. In this study, we focused on myeloid-derived suppressor cells (MDSCs; CD11bGr-1...
6.
Mikami N, Tani H, Kawakami R, Sugimoto A, Sakaguchi S, Ikuta T
Food Sci Nutr
. 2021 Jun;
9(6):3200-3208.
PMID: 34136184
FoxP3 regulatory T cells (Tregs) are needed to suppress inflammatory diseases and maintain immune homeostasis. The suppressive function of Tregs can be used to control autoimmune or inflammatory diseases; therefore,...
7.
Kawakami R, Kitagawa Y, Chen K, Arai M, Ohara D, Nakamura Y, et al.
Immunity
. 2021 Apr;
54(5):947-961.e8.
PMID: 33930308
The transcription factor Foxp3 plays crucial roles for Treg cell development and function. Conserved non-coding sequences (CNSs) at the Foxp3 locus control Foxp3 transcription, but how they developmentally contribute to...
8.
Inoue M, Yamashita K, Tsuji Y, Miki M, Amano S, Okumura T, et al.
J Immunol
. 2021 Mar;
206(8):1740-1751.
PMID: 33782090
Regulatory T cells (Tregs) are a subpopulation of lymphocytes that play a role in suppressing and regulating immune responses. Recently, it was suggested that controlling the functions and activities of...
9.
Yoshida Y, Mikami N, Nakanishi Y, Saimoto M, Nagaike A, Shimono H, et al.
Biol Pharm Bull
. 2021 Jan;
44(4):585-589.
PMID: 33504740
An increase in the number of glucocorticoid-induced tumor necrosis factor receptor-family related gene/protein (GITR)CD25 (or fork-head box protein 3: Foxp3) CD4 T cells, after treating a mouse model of arthritis...
10.
Mikami N, Kawakami R, Sakaguchi S
Curr Opin Immunol
. 2020 Aug;
67:36-41.
PMID: 32827951
Naturally occurring FoxP3CD4 regulatory T (Treg) cells indispensable for the maintenance of immunological self-tolerance and homeostasis are instrumental in treating autoimmune and other immunological disorders. Stable function of natural Treg...