Noriaki Takeguchi
Overview
Explore the profile of Noriaki Takeguchi including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
286
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Recent Articles
1.
Sakai H, Fujii T, Takeguchi N
Met Ions Life Sci
. 2016 Feb;
16:459-83.
PMID: 26860309
As a physiological phenomenon, acid secretion from the stomach was known already at least in the 17th century. But its mechanism was elucidated in more recent times only. At the...
2.
Fujii T, Takahashi Y, Takeshima H, Saitoh C, Shimizu T, Takeguchi N, et al.
Eur J Pharmacol
. 2015 Aug;
765:34-41.
PMID: 26277321
4-(2-Butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB) has been used as an inhibitor of volume-regulated anion channel (VRAC), which is expressed in almost all cells (IC50 is around 4 µM). Here, we found that...
3.
Fujita K, Fujii T, Shimizu T, Takeguchi N, Sakai H
Biochem Biophys Res Commun
. 2012 Jun;
424(1):136-40.
PMID: 22732406
K(+)-Cl(-) cotransporter-3a (KCC3a) is associated with Na(+),K(+)-ATPase α1-subunit (α1NaK) in lipid rafts of gastric acid-secreting cells and positively regulates Na(+),K(+)-ATPase activity. Here, effects of cholesterol on association of KCC3a with...
4.
Fujii T, Minagawa T, Shimizu T, Takeguchi N, Sakai H
J Physiol Sci
. 2011 Sep;
62(1):53-8.
PMID: 21932081
Effects of curcumin, a major constituent of turmeric, on ecto-nucleotidases have not been clarified. Here, we investigated whether curcumin affects ecto-nucleotidase activities in human hepatocellular carcinoma HepG2 cells. In the...
5.
Fujii T, Morii M, Takeguchi N, Sakai H
Nihon Yakurigaku Zasshi
. 2011 Aug;
138(2):51-5.
PMID: 21828937
No abstract available.
6.
Fujii T, Fujita K, Takeguchi N, Sakai H
Biol Pharm Bull
. 2011 Jun;
34(6):810-2.
PMID: 21628876
Gastric proton pump (H⁺, K⁺-ATPase) secretes H⁺ of acid (HCl) via the luminal membrane of parietal cells. For the HCl secretion, Cl⁻- and K⁺-transporting proteins are required. Recent our studies...
7.
Fujii T, Fujita K, Shimizu T, Takeguchi N, Sakai H
Biochem Biophys Res Commun
. 2010 Aug;
399(4):683-7.
PMID: 20691666
K(+)-Cl(-) cotransporter-3 has two major amino terminal variants, KCC3a and KCC3b. In LLC-PK1 cells, exogenously expressed KCC3a co-immunoprecipitated with endogenous Na(+),K(+)-ATPase alpha1-subunit (alpha1NaK), accompanying significant increases of the Na(+),K(+)-ATPase activity....
8.
Sakai H, Fujii T, Takeguchi N
Seikagaku
. 2009 Jun;
81(5):389-93.
PMID: 19522296
No abstract available.
9.
Watanabe T, Fujii T, Oya T, Horikawa N, Tabuchi Y, Takahashi Y, et al.
J Physiol Sci
. 2009 Apr;
59(2):113-22.
PMID: 19340551
Litttle is known about the function of aquaporin (AQP) water channels in human gastric cancer. In the upper or middle part of human stomach, we found that expression level of...
10.
Fujii T, Takahashi Y, Ikari A, Morii M, Tabuchi Y, Tsukada K, et al.
J Biol Chem
. 2008 Nov;
284(1):619-629.
PMID: 18984587
We studied whether K+-Cl(-) cotransporters (KCCs) are involved in gastric HCl secretion. We found that KCC4 is expressed in the gastric parietal cells more abundantly at the luminal region of...